Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome
<p>Abstract</p> <p>Background</p> <p>The Republic of Korea (South Korea) is one of the countries where vivax malaria had been successfully eradicated by the late 1970s. However, re-emergence of vivax malaria in South Korea was reported in 1993. Several epidemiological s...
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| Format: | Article |
| Language: | English |
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BMC
2010-06-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/9/1/184 |
| _version_ | 1818081583177924608 |
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| author | Iwagami Moritoshi Hwang Seung-Young Fukumoto Megumi Hayakawa Toshiyuki Tanabe Kazuyuki Kim So-Hee Kho Weon-Gyu Kano Shigeyuki |
| author_facet | Iwagami Moritoshi Hwang Seung-Young Fukumoto Megumi Hayakawa Toshiyuki Tanabe Kazuyuki Kim So-Hee Kho Weon-Gyu Kano Shigeyuki |
| author_sort | Iwagami Moritoshi |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The Republic of Korea (South Korea) is one of the countries where vivax malaria had been successfully eradicated by the late 1970s. However, re-emergence of vivax malaria in South Korea was reported in 1993. Several epidemiological studies and some genetic studies using antigenic molecules of <it>Plasmodium vivax </it>in the country have been reported, but the evolutionary history of <it>P. vivax </it>has not been fully understood. In this study, the origin of the South Korean <it>P. vivax </it>population was estimated by molecular phylogeographic analysis.</p> <p>Methods</p> <p>A haplotype network analysis based on <it>P. vivax </it>mitochondrial (mt) DNA sequences was conducted on 11 <it>P. vivax </it>isolates from South Korea and another 282 <it>P. vivax </it>isolates collected worldwide.</p> <p>Results</p> <p>The network analysis of <it>P. vivax </it>mtDNA sequences showed that the coexistence of two different groups (A and B) in South Korea. Groups A and B were identical or close to two different populations in southern China.</p> <p>Conclusions</p> <p>Although the direct introduction of the two <it>P. vivax </it>populations in South Korea were thought to have been from North Korea, the results of this analysis suggest the genealogical origin to be the two different populations in southern China.</p> |
| first_indexed | 2024-12-10T19:08:30Z |
| format | Article |
| id | doaj.art-e5f0c9b7b56841b8afdb6ad3dc4bff8a |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-10T19:08:30Z |
| publishDate | 2010-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-e5f0c9b7b56841b8afdb6ad3dc4bff8a2022-12-22T01:36:49ZengBMCMalaria Journal1475-28752010-06-019118410.1186/1475-2875-9-184Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genomeIwagami MoritoshiHwang Seung-YoungFukumoto MegumiHayakawa ToshiyukiTanabe KazuyukiKim So-HeeKho Weon-GyuKano Shigeyuki<p>Abstract</p> <p>Background</p> <p>The Republic of Korea (South Korea) is one of the countries where vivax malaria had been successfully eradicated by the late 1970s. However, re-emergence of vivax malaria in South Korea was reported in 1993. Several epidemiological studies and some genetic studies using antigenic molecules of <it>Plasmodium vivax </it>in the country have been reported, but the evolutionary history of <it>P. vivax </it>has not been fully understood. In this study, the origin of the South Korean <it>P. vivax </it>population was estimated by molecular phylogeographic analysis.</p> <p>Methods</p> <p>A haplotype network analysis based on <it>P. vivax </it>mitochondrial (mt) DNA sequences was conducted on 11 <it>P. vivax </it>isolates from South Korea and another 282 <it>P. vivax </it>isolates collected worldwide.</p> <p>Results</p> <p>The network analysis of <it>P. vivax </it>mtDNA sequences showed that the coexistence of two different groups (A and B) in South Korea. Groups A and B were identical or close to two different populations in southern China.</p> <p>Conclusions</p> <p>Although the direct introduction of the two <it>P. vivax </it>populations in South Korea were thought to have been from North Korea, the results of this analysis suggest the genealogical origin to be the two different populations in southern China.</p>http://www.malariajournal.com/content/9/1/184 |
| spellingShingle | Iwagami Moritoshi Hwang Seung-Young Fukumoto Megumi Hayakawa Toshiyuki Tanabe Kazuyuki Kim So-Hee Kho Weon-Gyu Kano Shigeyuki Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome Malaria Journal |
| title | Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome |
| title_full | Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome |
| title_fullStr | Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome |
| title_full_unstemmed | Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome |
| title_short | Geographical origin of <it>Plasmodium vivax </it>in the Republic of Korea: haplotype network analysis based on the parasite's mitochondrial genome |
| title_sort | geographical origin of it plasmodium vivax it in the republic of korea haplotype network analysis based on the parasite s mitochondrial genome |
| url | http://www.malariajournal.com/content/9/1/184 |
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