Blocking LFA-1 Aggravates Cardiac Inflammation in Experimental Autoimmune Myocarditis

Blocking LFA-1 Aggravates Cardiac Inflammation in Experimental Autoimmune Myocarditis

The lymphocyte function-associated antigen 1 (LFA-1) is a member of the beta2-integrin family and plays a pivotal role for T cell activation and leukocyte trafficking under inflammatory conditions. Blocking LFA-1 has reduced or aggravated inflammation depending on the inflammation model. To investig...

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Bibliographic Details
Main Authors: Ludwig T. Weckbach, Andreas Uhl, Felicitas Boehm, Valentina Seitelberger, Bruno C. Huber, Gabriela Kania, Stefan Brunner, Ulrich Grabmaier
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
myocarditis
inflammation
leukocytes
Online Access:https://www.mdpi.com/2073-4409/8/10/1267

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