RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase Modulates Neurite Outgrowth by Regulating the Expression of Spastin and p60-Katanin

RhoA-GTPase (RhoA) is widely regarded as a key molecular switch to inhibit neurite outgrowth by rigidifying the actin cytoskeleton. However, during neurite outgrowth, whether and how microtubule dynamics are regulated by RhoA remains to be elucidated. Herein, CT04 and Y27632 were used to inactivate...

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Bibliographic Details
Main Authors:	Dandan Tan, Haowen Zhang, Junyao Deng, Jingmin Liu, Jinkun Wen, Lixia Li, Xianghai Wang, Mengjie Pan, Xiaofang Hu, Jiasong Guo
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	Cells
Subjects:	neurite outgrowth rhoa signaling pathway spastin p60-katanin microtubule-severing proteins glu-tubulin
Online Access:	https://www.mdpi.com/2073-4409/9/1/230

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