NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads

NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads

Abstract Background Advances in whole genome sequencing strategies have provided the opportunity for genomic and comparative genomic analysis of a vast variety of organisms. The analysis results are highly dependent on the quality of the genome assemblies used. Assessment of the assembly accuracy ma...

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Bibliographic Details
Main Authors: Ksenia Khelik, Geir Kjetil Sandve, Alexander Johan Nederbragt, Torbjørn Rognes
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Genome assembly
Assembly errors
Illumina paired-end reads
Assembly accuracy assessment
Structural variant detection
Online Access:http://link.springer.com/article/10.1186/s12859-020-3414-0

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http://link.springer.com/article/10.1186/s12859-020-3414-0

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