Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered

Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription regulator that plays a pivotal role in coordinating the cellular response to oxidative stress. Through interactions with other proteins, such as Kelch-like ECH-associated protein 1 (Keap1), CREB-binding protein (CBP), and retinoid...

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Bibliographic Details
Main Authors: Nadun C. Karunatilleke, Courtney S. Fast, Vy Ngo, Anne Brickenden, Martin L. Duennwald, Lars Konermann, Wing-Yiu Choy
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
Nrf2
Keap1
nuclear magnetic resonance spectroscopy
hydrogen/deuterium exchange
mass spectrometry
Online Access:https://www.mdpi.com/1422-0067/22/14/7434

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