Genome-Wide Analysis of Methylation-Driven Genes and Identification of an Eight-Gene Panel for Prognosis Prediction in Breast Cancer

Genome-Wide Analysis of Methylation-Driven Genes and Identification of an Eight-Gene Panel for Prognosis Prediction in Breast Cancer

BackgroundAberrant DNA methylation is a crucial epigenetic regulator that is closely related to the occurrence and development of various cancers, including breast cancer (BC). The present study aimed to identify a novel methylation-based prognosis biomarker panel by integrally analyzing gene expres...

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Bibliographic Details
Main Authors: Yanshen Kuang, Ying Wang, Wanli Zhai, Xuning Wang, Bingdong Zhang, Maolin Xu, Shaohua Guo, Mu Ke, Baoqing Jia, Hongyi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
epigenetics
DNA methylation
breast cancer
prognosis biomarker
integrative analysis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00301/full

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