Rate and timing of cortical responses driven by separate sensory channels
The sense of touch comprises multiple sensory channels that each conveys characteristic signals during interactions with objects. These neural signals must then be integrated in such a way that behaviorally relevant information about the objects is preserved. To understand the process of integration...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2015-12-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/10450 |
| _version_ | 1811200404781793280 |
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| author | Hannes P Saal Michael A Harvey Sliman J Bensmaia |
| author_facet | Hannes P Saal Michael A Harvey Sliman J Bensmaia |
| author_sort | Hannes P Saal |
| collection | DOAJ |
| description | The sense of touch comprises multiple sensory channels that each conveys characteristic signals during interactions with objects. These neural signals must then be integrated in such a way that behaviorally relevant information about the objects is preserved. To understand the process of integration, we implement a simple computational model that describes how the responses of neurons in somatosensory cortex—recorded from awake, behaving monkeys—are shaped by the peripheral input, reconstructed using simulations of neuronal populations that reproduce natural spiking responses in the nerve with millisecond precision. First, we find that the strength of cortical responses is driven by one population of nerve fibers (rapidly adapting) whereas the timing of cortical responses is shaped by the other (Pacinian). Second, we show that input from these sensory channels is integrated in an optimal fashion that exploits the disparate response behaviors of different fiber types. |
| first_indexed | 2024-04-12T02:02:56Z |
| format | Article |
| id | doaj.art-e5fc8caff2fb4e54aedceb4fa2823d78 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T02:02:56Z |
| publishDate | 2015-12-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-e5fc8caff2fb4e54aedceb4fa2823d782022-12-22T03:52:37ZengeLife Sciences Publications LtdeLife2050-084X2015-12-01410.7554/eLife.10450Rate and timing of cortical responses driven by separate sensory channelsHannes P Saal0Michael A Harvey1Sliman J Bensmaia2Department of Organismal Biology and Anatomy, University of Chicago, Chicago, United StatesDepartment of Organismal Biology and Anatomy, University of Chicago, Chicago, United States; Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, United StatesDepartment of Organismal Biology and Anatomy, University of Chicago, Chicago, United States; Committee on Computational Neuroscience, University of Chicago, Chicago, United StatesThe sense of touch comprises multiple sensory channels that each conveys characteristic signals during interactions with objects. These neural signals must then be integrated in such a way that behaviorally relevant information about the objects is preserved. To understand the process of integration, we implement a simple computational model that describes how the responses of neurons in somatosensory cortex—recorded from awake, behaving monkeys—are shaped by the peripheral input, reconstructed using simulations of neuronal populations that reproduce natural spiking responses in the nerve with millisecond precision. First, we find that the strength of cortical responses is driven by one population of nerve fibers (rapidly adapting) whereas the timing of cortical responses is shaped by the other (Pacinian). Second, we show that input from these sensory channels is integrated in an optimal fashion that exploits the disparate response behaviors of different fiber types.https://elifesciences.org/articles/10450M. mulattatactilesensory integrationsomatosensorymechanoreceptorefficient coding |
| spellingShingle | Hannes P Saal Michael A Harvey Sliman J Bensmaia Rate and timing of cortical responses driven by separate sensory channels eLife M. mulatta tactile sensory integration somatosensory mechanoreceptor efficient coding |
| title | Rate and timing of cortical responses driven by separate sensory channels |
| title_full | Rate and timing of cortical responses driven by separate sensory channels |
| title_fullStr | Rate and timing of cortical responses driven by separate sensory channels |
| title_full_unstemmed | Rate and timing of cortical responses driven by separate sensory channels |
| title_short | Rate and timing of cortical responses driven by separate sensory channels |
| title_sort | rate and timing of cortical responses driven by separate sensory channels |
| topic | M. mulatta tactile sensory integration somatosensory mechanoreceptor efficient coding |
| url | https://elifesciences.org/articles/10450 |
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