Comparison the effectiveness of wavefront-guided and wavefront-optimized LASIK for myopia and myopic astigmatism

AIM:To compare the clinical outcomes of wavefront-guided and wavefront-optimized laser <i>in situ</i> keratomileusis(LASIK)to correct myopia and myopic astigmatism in patients with a preoperative total ocular higher-order aberrations(HOAs)lower than 0.3μm. <p>METHODS:In this prospe...

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Bibliographic Details
Main Authors: Xiao-Bin Zhao, Ke-Jun Li, Zhi-Hua Zhao, Zhi-Yang Jia
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-12-01
Series:Guoji Yanke Zazhi
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Online Access:http://ies.ijo.cn/cn_publish/2015/12/201512028.pdf
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Summary:AIM:To compare the clinical outcomes of wavefront-guided and wavefront-optimized laser <i>in situ</i> keratomileusis(LASIK)to correct myopia and myopic astigmatism in patients with a preoperative total ocular higher-order aberrations(HOAs)lower than 0.3μm. <p>METHODS:In this prospective study, 60 eyes of 30 patients with myopia with or without astigmatism in our department were included. One eye of each patient was randomized to undergo wavefront-guided LASIK, and the fellow eye received wavefront-optimized LASIK. Postoperative outcome measures at 6mo included visual acuity, refraction, ocular HOAs, and contrast sensitivity under mesopic condition. Paired <i>t</i>-test and <i>χ</i><sup>2</sup> test were used to analyze the data. <p>RESULTS:Six months postoperatively, 93% of eyes in the wavefront-guided group and 90% in the wavefront-optimized group had uncorrected visual acuity of 5.0 or better; 87% and 83%, respectively, had a postoperative spherical equivalent refraction of ±0.50D diopter. The differences were not statistically significant(<i>P</i>>0.05). No eye in either group lost 2 lines or more BCVA. Total HOAs, spherical aberration and coma increased in both groups postoperatively(<i>P</i><0.01), with no statistical differences in HOA changes between groups(<i>P</i>>0.05). Contrast sensitivity under mesopic conditions in both groups recovered to preoperative levels at all spatial frequencies at 6mo postoperative(<i>P</i>>0.05). <p>CONCLUSION:For eyes with preoperative HOAs lower than 0.3μm, wavefront-guided LASIK and wavefront-optimized LASIK can provide similar results in terms of visual acuity, refraction, HOAs, and contrast sensitivity.
ISSN:1672-5123
1672-5123