Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent Models
Rabies, a fatal disease in humans and other mammals, is caused by the rabies virus (RABV), and it poses a public health threat in many parts of the world. Once symptoms of rabies appear, the mortality is near 100%. There is currently no effective treatment for rabies. In our study, two human-derived...
Main Authors: | Fei Huang, Meishen Ren, Jie Pei, Hong Mei, Baokun Sui, Qiong Wu, Benjie Chai, Ruicheng Yang, Ming Zhou, Zhen F. Fu, Huiping Zhou, Ling Zhao |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2021.702273/full |
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