Antifungal peptides in marine invertebrates
A majority of terrestrial and marine organisms use to fend off a wide range of microorganisms, including bacteria and fungi by employing “antimicrobial peptides (AMPs)” that are ribosomally synthesized from proteinogenic amino acids. AMPs are a primary component of innate immune mechanisms in marine...
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| Format: | Article |
| Language: | English |
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University of Modena and Reggio Emilia
2009-12-01
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| Series: | Invertebrate Survival Journal |
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| Online Access: | https://isj02.unimore.it/index.php/ISJ/article/view/208 |
| _version_ | 1818823737397477376 |
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| author | N Fusetani |
| author_facet | N Fusetani |
| author_sort | N Fusetani |
| collection | DOAJ |
| description | A majority of terrestrial and marine organisms use to fend off a wide range of microorganisms, including bacteria and fungi by employing “antimicrobial peptides (AMPs)” that are ribosomally synthesized from proteinogenic amino acids. AMPs are a primary component of innate immune mechanisms in marine invertebrates. In contrast, marine sponges seem to contain no AMPs, but often contain nonribosomal peptides consisting of unusual amino acids that exhibit potent cytotoxic and antifungal activity. Most of these peptides are considered to be of symbiotic bacterial origin. Similarly opisthobranch molluscs sequester unusual bioactive nonribosomal peptides from their prey organisms, cyanobacteria. However, roles of these peptides are unknown. |
| first_indexed | 2024-12-18T23:44:44Z |
| format | Article |
| id | doaj.art-e60806a298c94dfea5c16e1e4f170c35 |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-18T23:44:44Z |
| publishDate | 2009-12-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-e60806a298c94dfea5c16e1e4f170c352022-12-21T20:47:15ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2009-12-0171Antifungal peptides in marine invertebratesN Fusetani0Faculty of Fisheries Sciences, Hokkaido University, Hakodate, 041-8611, JapanA majority of terrestrial and marine organisms use to fend off a wide range of microorganisms, including bacteria and fungi by employing “antimicrobial peptides (AMPs)” that are ribosomally synthesized from proteinogenic amino acids. AMPs are a primary component of innate immune mechanisms in marine invertebrates. In contrast, marine sponges seem to contain no AMPs, but often contain nonribosomal peptides consisting of unusual amino acids that exhibit potent cytotoxic and antifungal activity. Most of these peptides are considered to be of symbiotic bacterial origin. Similarly opisthobranch molluscs sequester unusual bioactive nonribosomal peptides from their prey organisms, cyanobacteria. However, roles of these peptides are unknown.https://isj02.unimore.it/index.php/ISJ/article/view/208nonribosomal peptideantifungal activityantimicrobial peptideinnate immunitymarine invertebrate |
| spellingShingle | N Fusetani Antifungal peptides in marine invertebrates Invertebrate Survival Journal nonribosomal peptide antifungal activity antimicrobial peptide innate immunity marine invertebrate |
| title | Antifungal peptides in marine invertebrates |
| title_full | Antifungal peptides in marine invertebrates |
| title_fullStr | Antifungal peptides in marine invertebrates |
| title_full_unstemmed | Antifungal peptides in marine invertebrates |
| title_short | Antifungal peptides in marine invertebrates |
| title_sort | antifungal peptides in marine invertebrates |
| topic | nonribosomal peptide antifungal activity antimicrobial peptide innate immunity marine invertebrate |
| url | https://isj02.unimore.it/index.php/ISJ/article/view/208 |
| work_keys_str_mv | AT nfusetani antifungalpeptidesinmarineinvertebrates |