CT findings of basaloid squamous cell carcinoma of the lung in 12 patients

Abstract. Basaloid squamous cell carcinoma (SCC) is very rare subtype of SCC of the lung and it is important to distinguish basaloid to other subtypes of SCCs, since the prognosis of basaloid subtype is considered poorer than that of other non-basaloid subtypes of SCCs. Aim of this study was to asse...

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Main Authors: Chu Hyun Kim, MD, Yoon Ki Cha, MD, Joungho Han, MD, PhD, Jun Ho Kim, MD, Tae Jung Kim, MD, PhD, Myung Jin Chung, MD, PhD, Jung Hee Lee, MD, PhD, Hyun Jung Yoon, MD, PhD, Hyunjin Park.
Format: Article
Language:English
Published: Wolters Kluwer 2022-05-01
Series:Medicine
Online Access:http://journals.lww.com/10.1097/MD.0000000000029197
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author Chu Hyun Kim, MD
Yoon Ki Cha, MD
Joungho Han, MD, PhD
Jun Ho Kim, MD
Tae Jung Kim, MD, PhD
Myung Jin Chung, MD, PhD
Jung Hee Lee, MD, PhD
Hyun Jung Yoon, MD, PhD
Hyunjin Park.
author_facet Chu Hyun Kim, MD
Yoon Ki Cha, MD
Joungho Han, MD, PhD
Jun Ho Kim, MD
Tae Jung Kim, MD, PhD
Myung Jin Chung, MD, PhD
Jung Hee Lee, MD, PhD
Hyun Jung Yoon, MD, PhD
Hyunjin Park.
author_sort Chu Hyun Kim, MD
collection DOAJ
description Abstract. Basaloid squamous cell carcinoma (SCC) is very rare subtype of SCC of the lung and it is important to distinguish basaloid to other subtypes of SCCs, since the prognosis of basaloid subtype is considered poorer than that of other non-basaloid subtypes of SCCs. Aim of this study was to assess computed tomography (CT) findings of basaloid SCC of the lung in 12 patients. From January 2016 to April 2021, 12 patients with surgically proven basaloid SCC of the lung were identified. CT findings were analyzed, and the imaging features were compared with histopathologic reports. Clinical and demographic features were also analyzed. Axial location of the tumor was central in 5 patients, while 7 was in peripheral. Of the 7 patients whose tumors were located in the peripheral, margin of the tumor were smooth (n = 2), lobulated (n = 2), or spiculated (n = 3). After contrast injection, net enhancement value ranged from 15.8 to 71.8 HU (median, 36.4 HU). Endobronchial growth were seen in 5 patients and these patients accompanied obstructive pneumonia or atelectasis. Internal profuse necrosis, cavitation, or calcifications were not seen. On CT, basaloid squamous cell presents as solitary nodule or mass with moderate enhancement. Tumor was located either peripheral or central compartment of the lung and cavitation was absent.
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spelling doaj.art-e60b9634525147b58e724dc5487628912022-12-22T00:30:51ZengWolters KluwerMedicine0025-79741536-59642022-05-0110119e2919710.1097/MD.0000000000029197202205130-00007CT findings of basaloid squamous cell carcinoma of the lung in 12 patientsChu Hyun Kim, MDYoon Ki Cha, MDJoungho Han, MD, PhDJun Ho Kim, MDTae Jung Kim, MD, PhDMyung Jin Chung, MD, PhDJung Hee Lee, MD, PhDHyun Jung Yoon, MD, PhDHyunjin Park.Abstract. Basaloid squamous cell carcinoma (SCC) is very rare subtype of SCC of the lung and it is important to distinguish basaloid to other subtypes of SCCs, since the prognosis of basaloid subtype is considered poorer than that of other non-basaloid subtypes of SCCs. Aim of this study was to assess computed tomography (CT) findings of basaloid SCC of the lung in 12 patients. From January 2016 to April 2021, 12 patients with surgically proven basaloid SCC of the lung were identified. CT findings were analyzed, and the imaging features were compared with histopathologic reports. Clinical and demographic features were also analyzed. Axial location of the tumor was central in 5 patients, while 7 was in peripheral. Of the 7 patients whose tumors were located in the peripheral, margin of the tumor were smooth (n = 2), lobulated (n = 2), or spiculated (n = 3). After contrast injection, net enhancement value ranged from 15.8 to 71.8 HU (median, 36.4 HU). Endobronchial growth were seen in 5 patients and these patients accompanied obstructive pneumonia or atelectasis. Internal profuse necrosis, cavitation, or calcifications were not seen. On CT, basaloid squamous cell presents as solitary nodule or mass with moderate enhancement. Tumor was located either peripheral or central compartment of the lung and cavitation was absent.http://journals.lww.com/10.1097/MD.0000000000029197
spellingShingle Chu Hyun Kim, MD
Yoon Ki Cha, MD
Joungho Han, MD, PhD
Jun Ho Kim, MD
Tae Jung Kim, MD, PhD
Myung Jin Chung, MD, PhD
Jung Hee Lee, MD, PhD
Hyun Jung Yoon, MD, PhD
Hyunjin Park.
CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
Medicine
title CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
title_full CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
title_fullStr CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
title_full_unstemmed CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
title_short CT findings of basaloid squamous cell carcinoma of the lung in 12 patients
title_sort ct findings of basaloid squamous cell carcinoma of the lung in 12 patients
url http://journals.lww.com/10.1097/MD.0000000000029197
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