Anti-inflammatory and anti-apoptotic effects of Zc3h12d against cerebral ischemia‒reperfusion through the modulation of the NF-κB signaling pathway

Anti-inflammatory and anti-apoptotic effects of Zc3h12d against cerebral ischemia‒reperfusion through the modulation of the NF-κB signaling pathway

Objective: Anti-inflammatory and anti-apoptotic therapy is expected to become the focus for attenuating cerebral ischemia‒reperfusion injury (CIRI), but the underlying mechanism needs to be further elucidated. Zc3h12d has been reported to downregulate NF-κB signaling pathway. Nevertheless, no studie...

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Bibliographic Details
Main Authors: Lijia Peng, Wenya Bai, Junjie Li, Li Xiong, Siying Huo, Jianlin Shao
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Brain Disorders
Subjects:
Zc3h12d
Cerebral ischemia‒reperfusion
Inflammation
Apoptosis
Nf-κb
Online Access:http://www.sciencedirect.com/science/article/pii/S2666459323000525

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