The Molecular Basis of Adenomyosis Development
Adenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Animal Reproduction and Biotechnology
2018-03-01
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| Series: | Journal of Animal Reproduction and Biotechnology |
| Subjects: | |
| Online Access: | http://www.e-jarb.org/journal/view.html?uid=37&vmd=Full |
| _version_ | 1818945058927280128 |
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| author | Woo Sub Yang Jeong Mook Lim Ji Yeon Ahn |
| author_facet | Woo Sub Yang Jeong Mook Lim Ji Yeon Ahn |
| author_sort | Woo Sub Yang |
| collection | DOAJ |
| description | Adenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain unclear. This paper summarizes the reports found in the MEDLINE database on the molecular mechanisms involved in the development and progression of uterine adenomyosis. The literature search included the following terms: “adenomyosis,” “adenomyoma,” “pathogenesis,” “molecular mechanisms,” and “gynecological disorders.” Only peer-reviewed, English-language journal articles were included. This review focuses on the molecular genetics, epigenetic modifications, and pivotal signaling pathways associated with adenomyosis development and progression, which will provide insights into and a better understanding of its underlying pathophysiology. |
| first_indexed | 2024-12-20T07:53:05Z |
| format | Article |
| id | doaj.art-e60fd7c780ff46a4b7eed4d60ae8baa4 |
| institution | Directory Open Access Journal |
| issn | 2671-4639 2671-4663 |
| language | English |
| last_indexed | 2024-12-20T07:53:05Z |
| publishDate | 2018-03-01 |
| publisher | The Korean Society of Animal Reproduction and Biotechnology |
| record_format | Article |
| series | Journal of Animal Reproduction and Biotechnology |
| spelling | doaj.art-e60fd7c780ff46a4b7eed4d60ae8baa42022-12-21T19:47:47ZengThe Korean Society of Animal Reproduction and BiotechnologyJournal of Animal Reproduction and Biotechnology2671-46392671-46632018-03-01331495410.12750/JET.2018.33.1.49The Molecular Basis of Adenomyosis DevelopmentWoo Sub Yang0Jeong Mook Lim1Ji Yeon Ahn2Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, KoreaDepartment of Agricultural Biotechnology, Seoul National University, Seoul 151-921, KoreaResearch Institutes of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, KoreaAdenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain unclear. This paper summarizes the reports found in the MEDLINE database on the molecular mechanisms involved in the development and progression of uterine adenomyosis. The literature search included the following terms: “adenomyosis,” “adenomyoma,” “pathogenesis,” “molecular mechanisms,” and “gynecological disorders.” Only peer-reviewed, English-language journal articles were included. This review focuses on the molecular genetics, epigenetic modifications, and pivotal signaling pathways associated with adenomyosis development and progression, which will provide insights into and a better understanding of its underlying pathophysiology.http://www.e-jarb.org/journal/view.html?uid=37&vmd=Fulladenomyosispathogenesismolecular mechanismsgynecological diseaseadenomyoma |
| spellingShingle | Woo Sub Yang Jeong Mook Lim Ji Yeon Ahn The Molecular Basis of Adenomyosis Development Journal of Animal Reproduction and Biotechnology adenomyosis pathogenesis molecular mechanisms gynecological disease adenomyoma |
| title | The Molecular Basis of Adenomyosis Development |
| title_full | The Molecular Basis of Adenomyosis Development |
| title_fullStr | The Molecular Basis of Adenomyosis Development |
| title_full_unstemmed | The Molecular Basis of Adenomyosis Development |
| title_short | The Molecular Basis of Adenomyosis Development |
| title_sort | molecular basis of adenomyosis development |
| topic | adenomyosis pathogenesis molecular mechanisms gynecological disease adenomyoma |
| url | http://www.e-jarb.org/journal/view.html?uid=37&vmd=Full |
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