Alterations in cellular metabolisms after TKI therapy for Philadelphia chromosome-positive leukemia in children: A review

Alterations in cellular metabolisms after TKI therapy for Philadelphia chromosome-positive leukemia in children: A review

Incidence rates of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) are lower but more aggressive in children than in adults due to different biological and host factors. After the clinical application of tyrosine kinase inhibitor (TKI) blo...

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Bibliographic Details
Main Authors:	Chunmou Li, Luping Wen, Junchao Dong, Lindi Li, Junbin Huang, Jing Yang, Tianqi Liang, Tianwen Li, Zhigang Xia, Chun Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Oncology
Subjects:	cellular metabolisms TKI therapy Philadelphia chromosome-positive leukemia children
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2022.1072806/full

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