Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease
Adult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary...
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Format: | Article |
Language: | English |
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MDPI AG
2022-04-01
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Series: | Journal of Clinical Medicine |
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Online Access: | https://www.mdpi.com/2077-0383/11/8/2232 |
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author | Nicolas Poursac Itsaso Odriozola Marie-Elise Truchetet |
author_facet | Nicolas Poursac Itsaso Odriozola Marie-Elise Truchetet |
author_sort | Nicolas Poursac |
collection | DOAJ |
description | Adult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary examinations, it is useful to advance in a structured manner, taking into consideration the actual added value of each supplemental examination. In this review, we detail the different complementary tests used in adult Still’s disease. We consider them from three different angles: positive diagnostic approach, the differential diagnosis, and the screening for complications of the disease. After discussing the various tests at our disposal, we look at the classical diagnostic strategy in order to propose a structured algorithm that can be used in clinical practice. We conclude with the prospects of new complementary examinations, which could in the future modify the management of patients. |
first_indexed | 2024-03-09T13:29:41Z |
format | Article |
id | doaj.art-e61579667a9641b383d12cdd3a3ce63d |
institution | Directory Open Access Journal |
issn | 2077-0383 |
language | English |
last_indexed | 2024-03-09T13:29:41Z |
publishDate | 2022-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Clinical Medicine |
spelling | doaj.art-e61579667a9641b383d12cdd3a3ce63d2023-11-30T21:19:58ZengMDPI AGJournal of Clinical Medicine2077-03832022-04-01118223210.3390/jcm11082232Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s DiseaseNicolas Poursac0Itsaso Odriozola1Marie-Elise Truchetet2Department of Rheumatology, FHU ACRONIM, University Hospital of Bordeaux, 33000 Bordeaux, FranceDepartment of Rheumatology, FHU ACRONIM, University Hospital of Bordeaux, 33000 Bordeaux, FranceDepartment of Rheumatology, FHU ACRONIM, University Hospital of Bordeaux, 33000 Bordeaux, FranceAdult-onset Still’s disease is a complex autoinflammatory disease with a multifactorial etiology. Its presentation is less stereotypical than that of a monogenic autoinflammatory disease and is actually relatively common with few specific signs. To avoid under- or over-prescription of complementary examinations, it is useful to advance in a structured manner, taking into consideration the actual added value of each supplemental examination. In this review, we detail the different complementary tests used in adult Still’s disease. We consider them from three different angles: positive diagnostic approach, the differential diagnosis, and the screening for complications of the disease. After discussing the various tests at our disposal, we look at the classical diagnostic strategy in order to propose a structured algorithm that can be used in clinical practice. We conclude with the prospects of new complementary examinations, which could in the future modify the management of patients.https://www.mdpi.com/2077-0383/11/8/2232adult-onset Still’s diseasebiological examinationradiological examinations |
spellingShingle | Nicolas Poursac Itsaso Odriozola Marie-Elise Truchetet Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease Journal of Clinical Medicine adult-onset Still’s disease biological examination radiological examinations |
title | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_full | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_fullStr | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_full_unstemmed | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_short | Strategy and Challenges of Paraclinical Examinations in Adult-Onset Still’s Disease |
title_sort | strategy and challenges of paraclinical examinations in adult onset still s disease |
topic | adult-onset Still’s disease biological examination radiological examinations |
url | https://www.mdpi.com/2077-0383/11/8/2232 |
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