Synthesis and characterisation of (Z)-styrylbenzene derivatives as potential selective anticancer agents

Synthesis and characterisation of (Z)-styrylbenzene derivatives as potential selective anticancer agents

To identify anticancer agents with high potency and low toxicity, a series of (Z)-styrylbenzene derivatives were synthesised and evaluated for anticancer activities using a panel of nine cancer cell lines and two noncancerous cell lines. Most derivatives exhibited significant anti-proliferative acti...

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Bibliographic Details
Main Authors: Ya-Bing Xin, Jia-Jun Li, Hong-Jian Zhang, Jun Ma, Xin Liu, Guo-Hua Gong, Yu-Shun Tian
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Styrylbenzene
cyano
selective toxic effect
anticancer
synthesis
Online Access:http://dx.doi.org/10.1080/14756366.2018.1513925

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