Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics

The past decades have seen tremendous progress in our understanding of the function of photoreceptors and olfactory sensory neurons, uncovering the mechanisms that determine their properties and, ultimately, our ability to see and smell. This progress has been driven to a large degree by the powerfu...

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Main Authors: Federica Genovese, Johannes Reisert, Vladimir J. Kefalov
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.761416/full
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author Federica Genovese
Johannes Reisert
Vladimir J. Kefalov
Vladimir J. Kefalov
author_facet Federica Genovese
Johannes Reisert
Vladimir J. Kefalov
Vladimir J. Kefalov
author_sort Federica Genovese
collection DOAJ
description The past decades have seen tremendous progress in our understanding of the function of photoreceptors and olfactory sensory neurons, uncovering the mechanisms that determine their properties and, ultimately, our ability to see and smell. This progress has been driven to a large degree by the powerful combination of physiological experimental tools and genetic manipulations, which has enabled us to identify the main molecular players in the transduction cascades of these sensory neurons, how their properties affect the detection and discrimination of stimuli, and how diseases affect our senses of vision and smell. This review summarizes some of the common and unique features of photoreceptors and olfactory sensory neurons that make these cells so exciting to study.
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spelling doaj.art-e62a6aa6acca47e9a56945e9d2b700d02022-12-21T23:13:58ZengFrontiers Media S.A.Frontiers in Cellular Neuroscience1662-51022021-10-011510.3389/fncel.2021.761416761416Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct CharacteristicsFederica Genovese0Johannes Reisert1Vladimir J. Kefalov2Vladimir J. Kefalov3Monell Chemical Senses Center, Philadelphia, PA, United StatesMonell Chemical Senses Center, Philadelphia, PA, United StatesDepartment of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, United StatesDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, United StatesThe past decades have seen tremendous progress in our understanding of the function of photoreceptors and olfactory sensory neurons, uncovering the mechanisms that determine their properties and, ultimately, our ability to see and smell. This progress has been driven to a large degree by the powerful combination of physiological experimental tools and genetic manipulations, which has enabled us to identify the main molecular players in the transduction cascades of these sensory neurons, how their properties affect the detection and discrimination of stimuli, and how diseases affect our senses of vision and smell. This review summarizes some of the common and unique features of photoreceptors and olfactory sensory neurons that make these cells so exciting to study.https://www.frontiersin.org/articles/10.3389/fncel.2021.761416/fullphotoreceptorrodconephototransductionolfactionolfactory sensory neuron
spellingShingle Federica Genovese
Johannes Reisert
Vladimir J. Kefalov
Vladimir J. Kefalov
Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
Frontiers in Cellular Neuroscience
photoreceptor
rod
cone
phototransduction
olfaction
olfactory sensory neuron
title Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
title_full Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
title_fullStr Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
title_full_unstemmed Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
title_short Sensory Transduction in Photoreceptors and Olfactory Sensory Neurons: Common Features and Distinct Characteristics
title_sort sensory transduction in photoreceptors and olfactory sensory neurons common features and distinct characteristics
topic photoreceptor
rod
cone
phototransduction
olfaction
olfactory sensory neuron
url https://www.frontiersin.org/articles/10.3389/fncel.2021.761416/full
work_keys_str_mv AT federicagenovese sensorytransductioninphotoreceptorsandolfactorysensoryneuronscommonfeaturesanddistinctcharacteristics
AT johannesreisert sensorytransductioninphotoreceptorsandolfactorysensoryneuronscommonfeaturesanddistinctcharacteristics
AT vladimirjkefalov sensorytransductioninphotoreceptorsandolfactorysensoryneuronscommonfeaturesanddistinctcharacteristics
AT vladimirjkefalov sensorytransductioninphotoreceptorsandolfactorysensoryneuronscommonfeaturesanddistinctcharacteristics