GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts.
Estrogens promote beneficial effects in the cardiovascular system mainly through the estrogen receptor (ER)α and ERβ, which act as ligand-gated transcription factors. Recently, the G protein-coupled estrogen receptor (GPER) has been implicated in the estrogenic signaling in diverse tissues, includin...
Main Authors: | Ernestina Marianna De Francesco, Tommaso Angelone, Teresa Pasqua, Marco Pupo, Maria Carmela Cerra, Marcello Maggiolini |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23950890/?tool=EBI |
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