Interferons in COVID-19: missed opportunities to prove efficacy in clinical phase III trials?
Interferons were repeatedly used in the therapy of COVID-19 due to their antiviral effects. Three recently published randomized controlled clinical phase III trials (WHO SOLIDARITY, ACTT-3, and SPRINTER) missed their primary objectives, i.e., a significant therapeutic effect of interferons was not d...
Main Authors: | Josef Brzoska, Harald von Eick, Manfred Hündgen |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-05-01
|
Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1198576/full |
Similar Items
-
Commentary: Why Haven’t We Found an Effective Treatment for COVID-19?
by: Josef Brzoska, et al.
Published: (2021-07-01) -
Editorial: Structures, Signaling Mechanisms, and Functions of Types I and III Interferons
by: Ronald L. Rabin, et al.
Published: (2021-02-01) -
Modern opportunities of interferons in treatment of children with COVID-19
by: Asiya I. Safina, et al.
Published: (2021-03-01) -
Insights Into Type I and III Interferons in Asthma and Exacerbations
by: Helen E. Rich, et al.
Published: (2020-09-01) -
Interferon-β 1a and SARS Coronavirus Replication
by: Lisa E. Hensley, et al.
Published: (2004-02-01)