Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders
<!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <styl...
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| Format: | Article |
| Language: | English |
| Published: |
Knowledge E
2009-04-01
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| Series: | Journal of Ophthalmic & Vision Research |
| Online Access: | http://www.jovr.ir/index.php/jovr/article/view/107 |
| _version_ | 1811332973659684864 |
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| author | Mansour Homayouni |
| author_facet | Mansour Homayouni |
| author_sort | Mansour Homayouni |
| collection | DOAJ |
| description | <!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <![endif]--> <p>The introduction of pharmacotherapy has been one of the most important advances in the management of retinal disorders. Age-related macular degeneration (AMD) was once considered as an irrepressible disease leading to permanent macular damage, however anti-vascular endothelial growth factor (anti-VEGF) agents are now believed to halt the progression of the condition and improve vision in a considerable proportion of patients. Anti-VEGF agents are among the most commonly used drugs in ophthalmology but questions and uncertainties still surround their indications, efficacy and complications. This paper reviews the role of VEGF under physiologic and pathologic conditions in the eye and available anti-VEGF agents in current ophthalmic practice.</p> |
| first_indexed | 2024-04-13T16:45:03Z |
| format | Article |
| id | doaj.art-e6372676339f49bc935265bb24d23406 |
| institution | Directory Open Access Journal |
| issn | 2008-2010 2008-322X |
| language | English |
| last_indexed | 2024-04-13T16:45:03Z |
| publishDate | 2009-04-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-e6372676339f49bc935265bb24d234062022-12-22T02:39:06ZengKnowledge EJournal of Ophthalmic & Vision Research2008-20102008-322X2009-04-0142105114Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular DisordersMansour Homayouni<!--[if gte mso 9]><xml> Normal 0 false false false MicrosoftInternetExplorer4 </xml><![endif]--><!--[if gte mso 9]><xml> </xml><![endif]--> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <![endif]--> <p>The introduction of pharmacotherapy has been one of the most important advances in the management of retinal disorders. Age-related macular degeneration (AMD) was once considered as an irrepressible disease leading to permanent macular damage, however anti-vascular endothelial growth factor (anti-VEGF) agents are now believed to halt the progression of the condition and improve vision in a considerable proportion of patients. Anti-VEGF agents are among the most commonly used drugs in ophthalmology but questions and uncertainties still surround their indications, efficacy and complications. This paper reviews the role of VEGF under physiologic and pathologic conditions in the eye and available anti-VEGF agents in current ophthalmic practice.</p>http://www.jovr.ir/index.php/jovr/article/view/107 |
| spellingShingle | Mansour Homayouni Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders Journal of Ophthalmic & Vision Research |
| title | Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders |
| title_full | Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders |
| title_fullStr | Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders |
| title_full_unstemmed | Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders |
| title_short | Vascular Endothelial Growth Factors and Their Inhibitors in Ocular Neovascular Disorders |
| title_sort | vascular endothelial growth factors and their inhibitors in ocular neovascular disorders |
| url | http://www.jovr.ir/index.php/jovr/article/view/107 |
| work_keys_str_mv | AT mansourhomayouni vascularendothelialgrowthfactorsandtheirinhibitorsinocularneovasculardisorders |