Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players

The dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level du...

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Main Authors: K. P. Bazarin, N. M. Titova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2014-05-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/1754
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author K. P. Bazarin
N. M. Titova
author_facet K. P. Bazarin
N. M. Titova
author_sort K. P. Bazarin
collection DOAJ
description The dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level during all the year. The maximum of MDA concentration is registered at the end of competition period and isn't restored during the period of rest. The SOD and CAT activity is significantly reduced and doesn't return to control levels during the year. These changes prove chronic decompensation in the antioxidant defense system. In athletes glutathione-S-transferase is the leading enzyme realizing protection against reactive oxygen species in blood serum of sportsmen. Compensatory increase of its activity is 660 % in reference to the level of control group.
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spelling doaj.art-e63733c8cee5482381641326988aba702024-03-28T07:49:12ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-05-01039131700Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby playersK. P. Bazarin0N. M. Titova1Scientific Institute of Medical Problems of the North SB RAMSSiberian Federal UniversityThe dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level during all the year. The maximum of MDA concentration is registered at the end of competition period and isn't restored during the period of rest. The SOD and CAT activity is significantly reduced and doesn't return to control levels during the year. These changes prove chronic decompensation in the antioxidant defense system. In athletes glutathione-S-transferase is the leading enzyme realizing protection against reactive oxygen species in blood serum of sportsmen. Compensatory increase of its activity is 660 % in reference to the level of control group.https://www.actabiomedica.ru/jour/article/view/1754sportphysical activityreactive oxygen speciesantioxidant defense system
spellingShingle K. P. Bazarin
N. M. Titova
Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
Acta Biomedica Scientifica
sport
physical activity
reactive oxygen species
antioxidant defense system
title Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
title_full Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
title_fullStr Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
title_full_unstemmed Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
title_short Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
title_sort dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
topic sport
physical activity
reactive oxygen species
antioxidant defense system
url https://www.actabiomedica.ru/jour/article/view/1754
work_keys_str_mv AT kpbazarin dynamicchangesinactivityofenzymesofantioxidantdefensesysteminbloodserumofprofessionalrugbyplayers
AT nmtitova dynamicchangesinactivityofenzymesofantioxidantdefensesysteminbloodserumofprofessionalrugbyplayers