Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players
The dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level du...
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Format: | Article |
Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2014-05-01
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Series: | Acta Biomedica Scientifica |
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Online Access: | https://www.actabiomedica.ru/jour/article/view/1754 |
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author | K. P. Bazarin N. M. Titova |
author_facet | K. P. Bazarin N. M. Titova |
author_sort | K. P. Bazarin |
collection | DOAJ |
description | The dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level during all the year. The maximum of MDA concentration is registered at the end of competition period and isn't restored during the period of rest. The SOD and CAT activity is significantly reduced and doesn't return to control levels during the year. These changes prove chronic decompensation in the antioxidant defense system. In athletes glutathione-S-transferase is the leading enzyme realizing protection against reactive oxygen species in blood serum of sportsmen. Compensatory increase of its activity is 660 % in reference to the level of control group. |
first_indexed | 2024-03-08T12:20:24Z |
format | Article |
id | doaj.art-e63733c8cee5482381641326988aba70 |
institution | Directory Open Access Journal |
issn | 2541-9420 2587-9596 |
language | Russian |
last_indexed | 2024-04-24T17:20:59Z |
publishDate | 2014-05-01 |
publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
record_format | Article |
series | Acta Biomedica Scientifica |
spelling | doaj.art-e63733c8cee5482381641326988aba702024-03-28T07:49:12ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-05-01039131700Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby playersK. P. Bazarin0N. M. Titova1Scientific Institute of Medical Problems of the North SB RAMSSiberian Federal UniversityThe dynamics of the level of malondialdehyde (MDA), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase was investigated in blood serum of professional rugby players during one year training and competitive season. The MDA level significantly exceeds control level during all the year. The maximum of MDA concentration is registered at the end of competition period and isn't restored during the period of rest. The SOD and CAT activity is significantly reduced and doesn't return to control levels during the year. These changes prove chronic decompensation in the antioxidant defense system. In athletes glutathione-S-transferase is the leading enzyme realizing protection against reactive oxygen species in blood serum of sportsmen. Compensatory increase of its activity is 660 % in reference to the level of control group.https://www.actabiomedica.ru/jour/article/view/1754sportphysical activityreactive oxygen speciesantioxidant defense system |
spellingShingle | K. P. Bazarin N. M. Titova Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players Acta Biomedica Scientifica sport physical activity reactive oxygen species antioxidant defense system |
title | Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
title_full | Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
title_fullStr | Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
title_full_unstemmed | Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
title_short | Dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
title_sort | dynamic changes in activity of enzymes of antioxidant defense system in blood serum of professional rugby players |
topic | sport physical activity reactive oxygen species antioxidant defense system |
url | https://www.actabiomedica.ru/jour/article/view/1754 |
work_keys_str_mv | AT kpbazarin dynamicchangesinactivityofenzymesofantioxidantdefensesysteminbloodserumofprofessionalrugbyplayers AT nmtitova dynamicchangesinactivityofenzymesofantioxidantdefensesysteminbloodserumofprofessionalrugbyplayers |