Obstructive sleep apnea and vascular disease

<p>Abstract</p> <p>There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as obesity. Even apparently healthy OSA patients have evidence of subtle functional vascular a...

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Main Authors: Somers Virend A, Lanfranchi Paola
Format: Article
Language:English
Published: BMC 2001-08-01
Series:Respiratory Research
Subjects:
Online Access:http://dx.doi.org/10.1186/rr79
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author Somers Virend A
Lanfranchi Paola
author_facet Somers Virend A
Lanfranchi Paola
author_sort Somers Virend A
collection DOAJ
description <p>Abstract</p> <p>There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as obesity. Even apparently healthy OSA patients have evidence of subtle functional vascular abnormalities that are known to occur in patients with hypertension and atherosclerosis. Untreated OSA may possibly contribute to the initiation and/or progression of pathophysiologic mechanisms involved in hypertension, heart failure, cardiac ischemia and stroke. This brief commentary will examine the evidence and mechanisms linking OSA to vascular disease.</p>
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spelling doaj.art-e63a1ee9efc440b29e433c983310e2e72022-12-22T03:07:21ZengBMCRespiratory Research1465-99212001-08-012631531910.1186/rr79Obstructive sleep apnea and vascular diseaseSomers Virend ALanfranchi Paola<p>Abstract</p> <p>There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as obesity. Even apparently healthy OSA patients have evidence of subtle functional vascular abnormalities that are known to occur in patients with hypertension and atherosclerosis. Untreated OSA may possibly contribute to the initiation and/or progression of pathophysiologic mechanisms involved in hypertension, heart failure, cardiac ischemia and stroke. This brief commentary will examine the evidence and mechanisms linking OSA to vascular disease.</p>http://dx.doi.org/10.1186/rr79cardiovascular riskhypertensionsleep apneasympathetic nervous systemvascular disease
spellingShingle Somers Virend A
Lanfranchi Paola
Obstructive sleep apnea and vascular disease
Respiratory Research
cardiovascular risk
hypertension
sleep apnea
sympathetic nervous system
vascular disease
title Obstructive sleep apnea and vascular disease
title_full Obstructive sleep apnea and vascular disease
title_fullStr Obstructive sleep apnea and vascular disease
title_full_unstemmed Obstructive sleep apnea and vascular disease
title_short Obstructive sleep apnea and vascular disease
title_sort obstructive sleep apnea and vascular disease
topic cardiovascular risk
hypertension
sleep apnea
sympathetic nervous system
vascular disease
url http://dx.doi.org/10.1186/rr79
work_keys_str_mv AT somersvirenda obstructivesleepapneaandvasculardisease
AT lanfranchipaola obstructivesleepapneaandvasculardisease