Research advances in the roles of local anesthetics in tumor metastasis and recurrence
Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioid...
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Format: | Article |
Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2022-03-01
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Series: | Jichu yixue yu linchuang |
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Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdf |
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author | LIU Chang, GUO Xiang-yang |
author_facet | LIU Chang, GUO Xiang-yang |
author_sort | LIU Chang, GUO Xiang-yang |
collection | DOAJ |
description | Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioids, but also inhibit tumor metastasis and recurrence by blocking sodium channels of cancer cells, changing epigenetics, decreasing inflammation and improving immune function. The exploration of the mechanism of local anesthetics in tumor metastasis and recurrence provides the new strategies for the optimal use of local anesthetics in cancer patient's perioperatively chemotherapy. |
first_indexed | 2024-03-08T16:56:21Z |
format | Article |
id | doaj.art-e63aa00a6b754e93a0c05bfdc02b3cee |
institution | Directory Open Access Journal |
issn | 1001-6325 |
language | zho |
last_indexed | 2024-03-08T16:56:21Z |
publishDate | 2022-03-01 |
publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
record_format | Article |
series | Jichu yixue yu linchuang |
spelling | doaj.art-e63aa00a6b754e93a0c05bfdc02b3cee2024-01-05T02:34:24ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-03-0142351251510.16352/j.issn.1001-6325.2022.03.015Research advances in the roles of local anesthetics in tumor metastasis and recurrenceLIU Chang, GUO Xiang-yang0Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, ChinaAnesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioids, but also inhibit tumor metastasis and recurrence by blocking sodium channels of cancer cells, changing epigenetics, decreasing inflammation and improving immune function. The exploration of the mechanism of local anesthetics in tumor metastasis and recurrence provides the new strategies for the optimal use of local anesthetics in cancer patient's perioperatively chemotherapy.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdfanesthesia|tumor|local anesthetics|metastasis and recurrence |
spellingShingle | LIU Chang, GUO Xiang-yang Research advances in the roles of local anesthetics in tumor metastasis and recurrence Jichu yixue yu linchuang anesthesia|tumor|local anesthetics|metastasis and recurrence |
title | Research advances in the roles of local anesthetics in tumor metastasis and recurrence |
title_full | Research advances in the roles of local anesthetics in tumor metastasis and recurrence |
title_fullStr | Research advances in the roles of local anesthetics in tumor metastasis and recurrence |
title_full_unstemmed | Research advances in the roles of local anesthetics in tumor metastasis and recurrence |
title_short | Research advances in the roles of local anesthetics in tumor metastasis and recurrence |
title_sort | research advances in the roles of local anesthetics in tumor metastasis and recurrence |
topic | anesthesia|tumor|local anesthetics|metastasis and recurrence |
url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdf |
work_keys_str_mv | AT liuchangguoxiangyang researchadvancesintherolesoflocalanestheticsintumormetastasisandrecurrence |