Research advances in the roles of local anesthetics in tumor metastasis and recurrence

Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioid...

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Main Author: LIU Chang, GUO Xiang-yang
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-03-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdf
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author LIU Chang, GUO Xiang-yang
author_facet LIU Chang, GUO Xiang-yang
author_sort LIU Chang, GUO Xiang-yang
collection DOAJ
description Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioids, but also inhibit tumor metastasis and recurrence by blocking sodium channels of cancer cells, changing epigenetics, decreasing inflammation and improving immune function. The exploration of the mechanism of local anesthetics in tumor metastasis and recurrence provides the new strategies for the optimal use of local anesthetics in cancer patient's perioperatively chemotherapy.
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publishDate 2022-03-01
publisher Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
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series Jichu yixue yu linchuang
spelling doaj.art-e63aa00a6b754e93a0c05bfdc02b3cee2024-01-05T02:34:24ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-03-0142351251510.16352/j.issn.1001-6325.2022.03.015Research advances in the roles of local anesthetics in tumor metastasis and recurrenceLIU Chang, GUO Xiang-yang0Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, ChinaAnesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer. Perioperative applications of local anesthetics can not only reduce the amount of opioids, but also inhibit tumor metastasis and recurrence by blocking sodium channels of cancer cells, changing epigenetics, decreasing inflammation and improving immune function. The exploration of the mechanism of local anesthetics in tumor metastasis and recurrence provides the new strategies for the optimal use of local anesthetics in cancer patient's perioperatively chemotherapy.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdfanesthesia|tumor|local anesthetics|metastasis and recurrence
spellingShingle LIU Chang, GUO Xiang-yang
Research advances in the roles of local anesthetics in tumor metastasis and recurrence
Jichu yixue yu linchuang
anesthesia|tumor|local anesthetics|metastasis and recurrence
title Research advances in the roles of local anesthetics in tumor metastasis and recurrence
title_full Research advances in the roles of local anesthetics in tumor metastasis and recurrence
title_fullStr Research advances in the roles of local anesthetics in tumor metastasis and recurrence
title_full_unstemmed Research advances in the roles of local anesthetics in tumor metastasis and recurrence
title_short Research advances in the roles of local anesthetics in tumor metastasis and recurrence
title_sort research advances in the roles of local anesthetics in tumor metastasis and recurrence
topic anesthesia|tumor|local anesthetics|metastasis and recurrence
url http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-3-512.pdf
work_keys_str_mv AT liuchangguoxiangyang researchadvancesintherolesoflocalanestheticsintumormetastasisandrecurrence