EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN

Objective: To study the results of long continuous comprehensive treatment of osteoporosis in multiparous women on the background degenerative and dystrophic skeletal changes in the postmenopausal period. Methods: A retrospective analysis of the results of treatment of 53 multiparous women on the...

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Main Authors: I.G. MUKHAMEDOVA, A.A. RAZZOKOV, A S. EKHSONOV
Format: Article
Language:English
Published: Avicenna Tajik State Medical University 2019-06-01
Series:Паёми Сино
Subjects:
Online Access:https://doi.org/%2010.25005/2074-0581-2019-21-2-274-278
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author I.G. MUKHAMEDOVA
A.A. RAZZOKOV
A S. EKHSONOV
author_facet I.G. MUKHAMEDOVA
A.A. RAZZOKOV
A S. EKHSONOV
author_sort I.G. MUKHAMEDOVA
collection DOAJ
description Objective: To study the results of long continuous comprehensive treatment of osteoporosis in multiparous women on the background degenerative and dystrophic skeletal changes in the postmenopausal period. Methods: A retrospective analysis of the results of treatment of 53 multiparous women on the background of degenerative and dystrophic skeletal changes in the postmenopausal period assessment in the dynamics of the level of Ca and Mg in serum, bone mineral density in the vertebral segment and proximal hip. Results: It was found that after 3-6-18 months of treatment in 41 (77.4%) pain relief was observed, in 38 (71.1%) of serum calcium and magnesium increased in the case. X-ray showed marked increased clarity of the contours of the bones of the skeleton and an increase in bone mineral density (BMD) at the level of the vertebral segment by 7.4% (р<0.001) and in the proximal hip 3.6% (p<0.05). Conclusion: The results of the study show that long continuous intake of antiresorptive drugs contributes to the activation of the process of bone remodeling, prevent further bone loss and achieve non-osteoporotic T-criterion values
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spelling doaj.art-e640902e96e044f88bde02f9a5f68c902023-06-22T19:01:36ZengAvicenna Tajik State Medical UniversityПаёми Сино2074-05812959-63272019-06-0121227427810.25005/2074-0581-2019-21-2-274-278EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMENI.G. MUKHAMEDOVA0A.A. RAZZOKOV1A S. EKHSONOV2Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of TajikistanDepartment of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of TajikistanDepartment of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of TajikistanObjective: To study the results of long continuous comprehensive treatment of osteoporosis in multiparous women on the background degenerative and dystrophic skeletal changes in the postmenopausal period. Methods: A retrospective analysis of the results of treatment of 53 multiparous women on the background of degenerative and dystrophic skeletal changes in the postmenopausal period assessment in the dynamics of the level of Ca and Mg in serum, bone mineral density in the vertebral segment and proximal hip. Results: It was found that after 3-6-18 months of treatment in 41 (77.4%) pain relief was observed, in 38 (71.1%) of serum calcium and magnesium increased in the case. X-ray showed marked increased clarity of the contours of the bones of the skeleton and an increase in bone mineral density (BMD) at the level of the vertebral segment by 7.4% (р<0.001) and in the proximal hip 3.6% (p<0.05). Conclusion: The results of the study show that long continuous intake of antiresorptive drugs contributes to the activation of the process of bone remodeling, prevent further bone loss and achieve non-osteoporotic T-criterion valueshttps://doi.org/%2010.25005/2074-0581-2019-21-2-274-278osteoporosisosteopeniabone mineral densitypostmenopausal periodcalcium.
spellingShingle I.G. MUKHAMEDOVA
A.A. RAZZOKOV
A S. EKHSONOV
EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
Паёми Сино
osteoporosis
osteopenia
bone mineral density
postmenopausal period
calcium.
title EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
title_full EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
title_fullStr EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
title_full_unstemmed EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
title_short EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
title_sort evaluation of the efficiency of antiresorptive therapy for osteoporosis in multiparous women
topic osteoporosis
osteopenia
bone mineral density
postmenopausal period
calcium.
url https://doi.org/%2010.25005/2074-0581-2019-21-2-274-278
work_keys_str_mv AT igmukhamedova evaluationoftheefficiencyofantiresorptivetherapyforosteoporosisinmultiparouswomen
AT aarazzokov evaluationoftheefficiencyofantiresorptivetherapyforosteoporosisinmultiparouswomen
AT asekhsonov evaluationoftheefficiencyofantiresorptivetherapyforosteoporosisinmultiparouswomen