First-line induction chemotherapy with high-dose methotrexate versus teniposide in patients with newly diagnosed primary central nervous system lymphoma: a retrospective, multicenter cohort study

First-line induction chemotherapy with high-dose methotrexate versus teniposide in patients with newly diagnosed primary central nervous system lymphoma: a retrospective, multicenter cohort study

Abstract Background This study aimed to compare the efficacy and safety of high-dose methotrexate (HD-MTX) versus teniposide (TEN) in patients with newly diagnosed immunocompetent primary central nervous system lymphomas (PCNSLs). Methods The study included immunocompetent, adult patients with newly...

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Bibliographic Details
Main Authors: Kaili Zhong, Yanyan Shi, Yuhuan Gao, Huilai Zhang, Mingzhi Zhang, Qiaohua Zhang, Xinan Cen, Mei Xue, Yan Qin, Yu Zhao, Liling Zhang, Rong Liang, Ningju Wang, Yan Xie, Yu Yang, Aichun Liu, Huizheng Bao, Jingwen Wang, Baoping Cao, Wei Zhang, Weijing Zhang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Cancer
Subjects:
First-line induction chemotherapy
Methotrexate
Primary central nervous system lymphoma
Teniposide
Online Access:https://doi.org/10.1186/s12885-023-11268-5

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