Tolperisone in the treatment of acute and chronic nonspecific back pain
Nonspecific back pain (NBP) is one of the most common reasons to see a neurologist or therapist. Acute (<4 weeks' duration), subacute (4 to 12 weeks), and chronic (>12 weeks) NBPs are recognized. The diagnosis of NBP is based on anamnestic data, somatic, neurological, and neurolog...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2020-08-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
| Subjects: | |
| Online Access: | https://nnp.ima-press.net/nnp/article/view/1418 |
| _version_ | 1827062813805248512 |
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| author | V. A. Golovacheva A. A. Golovacheva O. E. Zinovyeva V. L. Golubev |
| author_facet | V. A. Golovacheva A. A. Golovacheva O. E. Zinovyeva V. L. Golubev |
| author_sort | V. A. Golovacheva |
| collection | DOAJ |
| description | Nonspecific back pain (NBP) is one of the most common reasons to see a neurologist or therapist. Acute (<4 weeks' duration), subacute (4 to 12 weeks), and chronic (>12 weeks) NBPs are recognized. The diagnosis of NBP is based on anamnestic data, somatic, neurological, and neurologic-and-orthopedic examination findings and on the exclusion of the specific causes of back pain, discogenic radiculopathy, and vertebral canal stenosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants are used in the pharmacotherapy of acute, subacute, and chronic NBP. Tolperisone is widely used as a muscle relaxant in Russia and in the countries of Europe and Asia. Clinical trials have shown the efficacy and good tolerance of tolperisone used alone and in combination with NSAIDs for NBP. The review presents clinical recommendations from different countries on the use of muscle relaxants in the treatment of acute and chronic NBP. It is concluded that a large-scale qualitative randomized trial should be conducted to investigate the efficacy of muscle relaxants, tolperisone in particular, in the treatment of acute, subacute, and chronic NBP. |
| first_indexed | 2024-04-10T02:01:25Z |
| format | Article |
| id | doaj.art-e643c3e41e144143a64de879c5effc58 |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2025-02-18T20:01:51Z |
| publishDate | 2020-08-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-e643c3e41e144143a64de879c5effc582024-10-17T16:15:27ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422020-08-0112413714210.14412/2074-2711-2020-4-137-1421034Tolperisone in the treatment of acute and chronic nonspecific back painV. A. Golovacheva0A. A. Golovacheva1O. E. Zinovyeva2V. L. Golubev3I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaNonspecific back pain (NBP) is one of the most common reasons to see a neurologist or therapist. Acute (<4 weeks' duration), subacute (4 to 12 weeks), and chronic (>12 weeks) NBPs are recognized. The diagnosis of NBP is based on anamnestic data, somatic, neurological, and neurologic-and-orthopedic examination findings and on the exclusion of the specific causes of back pain, discogenic radiculopathy, and vertebral canal stenosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants are used in the pharmacotherapy of acute, subacute, and chronic NBP. Tolperisone is widely used as a muscle relaxant in Russia and in the countries of Europe and Asia. Clinical trials have shown the efficacy and good tolerance of tolperisone used alone and in combination with NSAIDs for NBP. The review presents clinical recommendations from different countries on the use of muscle relaxants in the treatment of acute and chronic NBP. It is concluded that a large-scale qualitative randomized trial should be conducted to investigate the efficacy of muscle relaxants, tolperisone in particular, in the treatment of acute, subacute, and chronic NBP.https://nnp.ima-press.net/nnp/article/view/1418back painacute painchronic paintreatmentmuscle relaxantstolperisone |
| spellingShingle | V. A. Golovacheva A. A. Golovacheva O. E. Zinovyeva V. L. Golubev Tolperisone in the treatment of acute and chronic nonspecific back pain Неврология, нейропсихиатрия, психосоматика back pain acute pain chronic pain treatment muscle relaxants tolperisone |
| title | Tolperisone in the treatment of acute and chronic nonspecific back pain |
| title_full | Tolperisone in the treatment of acute and chronic nonspecific back pain |
| title_fullStr | Tolperisone in the treatment of acute and chronic nonspecific back pain |
| title_full_unstemmed | Tolperisone in the treatment of acute and chronic nonspecific back pain |
| title_short | Tolperisone in the treatment of acute and chronic nonspecific back pain |
| title_sort | tolperisone in the treatment of acute and chronic nonspecific back pain |
| topic | back pain acute pain chronic pain treatment muscle relaxants tolperisone |
| url | https://nnp.ima-press.net/nnp/article/view/1418 |
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