TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism

The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A persisting optic fissure, coloboma, is a major cause for blindness in children. Although many genes have been linked to coloboma, the process of optic fissure fusion is still little...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Max D. Knickmeyer, Juan L. Mateo, Priska Eckert, Eleni Roussa, Belal Rahhal, Aimee Zuniga, Kerstin Krieglstein, Joachim Wittbrodt, Stephan Heermann
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: The Royal Society 2018-03-01
Σειρά:Open Biology
Θέματα:
Διαθέσιμο Online:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170134