Clinical Pathobiochemistry of Vitamin B<sub>12</sub> Deficiency: Improving Our Understanding by Exploring Novel Mechanisms with a Focus on Diabetic Neuropathy

Clinical Pathobiochemistry of Vitamin B<sub>12</sub> Deficiency: Improving Our Understanding by Exploring Novel Mechanisms with a Focus on Diabetic Neuropathy

Vitamin B<sub>12</sub> (B<sub>12</sub>) is an essential cofactor of two important biochemical pathways, the degradation of methylmalonic acid and the synthesis of methionine from homocysteine. Methionine is an important donor of methyl groups for numerous biochemical reaction...

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Bibliographic Details
Main Authors: Erwin Schleicher, Triantafyllos Didangelos, Evangelia Kotzakioulafi, Alexander Cegan, Andreas Peter, Konstantinos Kantartzis
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Nutrients
Subjects:
cobalamin
diabetes
homocysteine
methylmalonic acid
peripheral neuropathy
laboratory biomarker
Online Access:https://www.mdpi.com/2072-6643/15/11/2597

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