T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 <named-content content-type="genus-species">Streptococcus pyogenes</named-content>

T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 <named-content content-type="genus-species">Streptococcus pyogenes</named-content>

ABSTRACT Streptococcus pyogenes (group A Streptococcus [GAS]) is an important human pathogen causing a broad spectrum of diseases and associated with significant global morbidity and mortality. Almost all GAS isolates express a surface hyaluronic acid capsule, a virulence determinant that facilitate...

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Bibliographic Details
Main Authors: Yi-Hsuan Chen, Shao-Hui Li, Yao-Cheng Yang, Shu-Hao Hsu, Victor Nizet, Yung-Chi Chang
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
Streptococcus pyogenes
group A Streptococcus
pilus
T antigen
haptoglobin
innate immunity
Online Access:https://journals.asm.org/doi/10.1128/mBio.01580-20

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