Optimal anti-amyloid-beta therapy for Alzheimer's disease via a personalized mathematical model.
With the recent approval by the FDA of the first disease-modifying drug for Alzheimer's Disease (AD), personalized medicine will be increasingly important for appropriate management and counseling of patients with AD and those at risk. The growing availability of clinical biomarker data and dat...
Main Authors: | Wenrui Hao, Suzanne Lenhart, Jeffrey R Petrella |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-09-01
|
Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010481 |
Similar Items
-
Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis
by: Ernesto Fedele
Published: (2023-09-01) -
Amyloid beta and Alzheimer’s Disease: The role of neprilysin-2 in amyloid-beta clearance
by: Robert eMarr, et al.
Published: (2014-08-01) -
Amyloid Beta in Aging and Alzheimer’s Disease
by: Ujala Sehar, et al.
Published: (2022-10-01) -
BETA-AMYLOID AS PATHOGENESIS OF ALZHEIMER DISEASE
by: Kadek Ary Mahendri Pattni
Published: (2013-07-01) -
Current Anti-Amyloid-β Therapy for Alzheimer’s Disease Treatment: From Clinical Research to Nanomedicine
by: Zhao Z, et al.
Published: (2023-12-01)