Bazex-syndrome with esophageal cancer

Skin diseases can be a first sign of internal malignancies. Acrokeratosis neoplastica or Bazex-syndrome is a rare obligatory paraneoplastic dermatosis. We report on a 51-year-old male patient who complaint about reduced physical working capacity, swelling of fingers and toes. He presented with non-i...

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Main Authors: Sebastian Boldt, Uwe Wollina
Format: Article
Language:English
Published: Our Dermatology Online 2016-10-01
Series:Nasza Dermatologia Online
Subjects:
Online Access:http://www.odermatol.com/issue-in-html/2016-4-8-bazex/
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author Sebastian Boldt
Uwe Wollina
author_facet Sebastian Boldt
Uwe Wollina
author_sort Sebastian Boldt
collection DOAJ
description Skin diseases can be a first sign of internal malignancies. Acrokeratosis neoplastica or Bazex-syndrome is a rare obligatory paraneoplastic dermatosis. We report on a 51-year-old male patient who complaint about reduced physical working capacity, swelling of fingers and toes. He presented with non-itching violaceous erythemato-squamous lesions on nose, hands and feet. On examination we observed onychomadesis of finger nails. Thoracic computerized tomography disclosed a tumor mass in the distal esophagus. Endosonography with trans-esophageal fine-needle biopsy confirmed the diagnosis of esophageal squamous cell carcinoma. The knowledge of cutaneous paraneoplasias allows an earlier diagnosis of internal malignancies.
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spelling doaj.art-e6554eccc9444834b358d599c9555f532022-12-22T03:43:40ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902016-10-017440340510.7241/ourd.20164.110Bazex-syndrome with esophageal cancerSebastian Boldt0Uwe Wollina1Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, GermanyDepartment of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, 01067 Dresden, GermanySkin diseases can be a first sign of internal malignancies. Acrokeratosis neoplastica or Bazex-syndrome is a rare obligatory paraneoplastic dermatosis. We report on a 51-year-old male patient who complaint about reduced physical working capacity, swelling of fingers and toes. He presented with non-itching violaceous erythemato-squamous lesions on nose, hands and feet. On examination we observed onychomadesis of finger nails. Thoracic computerized tomography disclosed a tumor mass in the distal esophagus. Endosonography with trans-esophageal fine-needle biopsy confirmed the diagnosis of esophageal squamous cell carcinoma. The knowledge of cutaneous paraneoplasias allows an earlier diagnosis of internal malignancies.http://www.odermatol.com/issue-in-html/2016-4-8-bazex/Paraneoplastic skin disease; Acrokeratosis neoplastica; Bazex-syndrome
spellingShingle Sebastian Boldt
Uwe Wollina
Bazex-syndrome with esophageal cancer
Nasza Dermatologia Online
Paraneoplastic skin disease; Acrokeratosis neoplastica; Bazex-syndrome
title Bazex-syndrome with esophageal cancer
title_full Bazex-syndrome with esophageal cancer
title_fullStr Bazex-syndrome with esophageal cancer
title_full_unstemmed Bazex-syndrome with esophageal cancer
title_short Bazex-syndrome with esophageal cancer
title_sort bazex syndrome with esophageal cancer
topic Paraneoplastic skin disease; Acrokeratosis neoplastica; Bazex-syndrome
url http://www.odermatol.com/issue-in-html/2016-4-8-bazex/
work_keys_str_mv AT sebastianboldt bazexsyndromewithesophagealcancer
AT uwewollina bazexsyndromewithesophagealcancer