Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation
Abstract Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis. In this study, we treated bone marrow cells (BMCs) from mice with purified α-toxin and found that TER119+ erythroblasts were great...
Main Authors: | Teruhisa Takagishi, Masaya Takehara, Soshi Seike, Kazuaki Miyamoto, Keiko Kobayashi, Masahiro Nagahama |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05567-8 |
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