Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet

Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet

<p>Abstract</p> <p>Background</p> <p>Statins are first-line pharmacotherapeutic agents for hypercholesterolemia treatment in humans. However the effects of statins on atherosclerosis in mouse models are very paradoxical. In this work, we wanted to evaluate the effects o...

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Bibliographic Details
Main Authors:	Tian Hua, Yu Yang, Zhao Zhenmei, Liu Jia, Song Guohua, Yao Shutong, Li Guoli, Qin Shucun
Format:	Article
Language:	English
Published:	BMC 2011-01-01
Series:	Lipids in Health and Disease
Online Access:	http://www.lipidworld.com/content/10/1/8

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