A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation
Abstract Background Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. ACCs are classified as functioning and non-functioning. The pathogenesis of ACC remains elusive, and diagnosis of ACC is currently based on pathology. In the absence of other effective appro...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-03-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12957-018-1326-5 |
| _version_ | 1818258059038818304 |
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| author | Kai Kou Haiwen Zhang Conggui Zhang Enbo Xie Yuguo Chen Guangyi Wang Guoyue Lv |
| author_facet | Kai Kou Haiwen Zhang Conggui Zhang Enbo Xie Yuguo Chen Guangyi Wang Guoyue Lv |
| author_sort | Kai Kou |
| collection | DOAJ |
| description | Abstract Background Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. ACCs are classified as functioning and non-functioning. The pathogenesis of ACC remains elusive, and diagnosis of ACC is currently based on pathology. In the absence of other effective approaches, surgical resection is the preferred treatment option. Case presentation Here, we report a case of ACC in the retroperitoneum. The patient underwent radical adrenalectomy and remained disease-free throughout a 6-month follow-up. Conclusions Radical surgical resection is an efficient therapy for ACC, and hydrocortisone can be used to alleviate symptoms of secondary acute adrenal hypofunction. |
| first_indexed | 2024-12-12T17:53:31Z |
| format | Article |
| id | doaj.art-e65ab2fa679d48b2b4384326d7ec6389 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-12T17:53:31Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-e65ab2fa679d48b2b4384326d7ec63892022-12-22T00:16:46ZengBMCWorld Journal of Surgical Oncology1477-78192018-03-011611410.1186/s12957-018-1326-5A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperationKai Kou0Haiwen Zhang1Conggui Zhang2Enbo Xie3Yuguo Chen4Guangyi Wang5Guoyue Lv6Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Department of Hepatobiliary and Pancreatic Surgery, Bethune Hospital 1Abstract Background Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. ACCs are classified as functioning and non-functioning. The pathogenesis of ACC remains elusive, and diagnosis of ACC is currently based on pathology. In the absence of other effective approaches, surgical resection is the preferred treatment option. Case presentation Here, we report a case of ACC in the retroperitoneum. The patient underwent radical adrenalectomy and remained disease-free throughout a 6-month follow-up. Conclusions Radical surgical resection is an efficient therapy for ACC, and hydrocortisone can be used to alleviate symptoms of secondary acute adrenal hypofunction.http://link.springer.com/article/10.1186/s12957-018-1326-5Adrenocortical carcinomaDiagnosisTherapyImmunohistochemistryMitotane |
| spellingShingle | Kai Kou Haiwen Zhang Conggui Zhang Enbo Xie Yuguo Chen Guangyi Wang Guoyue Lv A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation World Journal of Surgical Oncology Adrenocortical carcinoma Diagnosis Therapy Immunohistochemistry Mitotane |
| title | A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| title_full | A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| title_fullStr | A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| title_full_unstemmed | A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| title_short | A case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| title_sort | case of adrenocortical carcinoma accompanying secondary acute adrenal hypofunction postoperation |
| topic | Adrenocortical carcinoma Diagnosis Therapy Immunohistochemistry Mitotane |
| url | http://link.springer.com/article/10.1186/s12957-018-1326-5 |
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