THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE
Parkinson's disease (PD) is the second most common neurodegenerative disorder after the dementia of Alzheimer. The clinical presentation of PD is dominated by typical motor symptoms as resting tremor, cogwheel rigidity, bradykinesia, and postural instability. Non-motor symptoms (NMS) of Parkins...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2020-11-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | https://www.journal-imab-bg.org/issues-2020/issue4/2020vol26-issue4-3469-3474.pdf |
| _version_ | 1818352496459907072 |
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| author | Desislava Marinova Maya Danovska |
| author_facet | Desislava Marinova Maya Danovska |
| author_sort | Desislava Marinova |
| collection | DOAJ |
| description | Parkinson's disease (PD) is the second most common neurodegenerative disorder after the dementia of Alzheimer. The clinical presentation of PD is dominated by typical motor symptoms as resting tremor, cogwheel rigidity, bradykinesia, and postural instability. Non-motor symptoms (NMS) of Parkinson's disease are common but are often under-recognized in clinical practice either due to the lack of spontaneous complaints by the patients or to the absence of systematic questioning by healthcare professionals. In contrast to motor dysfunctions, non-motor symptoms frequently remain unreported. Recently, a self-completed NMS questionnaire and NMS scale for identification and evaluation of these symptoms have been validated. An international survey has shown that up to 62% of NMS in PD remain undeclared to healthcare professionals because patients are unaware that NMS symptoms are linked to PD. Based on both clinical and neuropathological data, PD, traditionally accepted as a dopaminergic motor disorder, now can be characterized as a multisystem neurodegenerative disease that involves many neurotransmitter systems and affects not only motor but non-motor functions, too. |
| first_indexed | 2024-12-13T18:54:34Z |
| format | Article |
| id | doaj.art-e65bb6c2190a4d5587d430779050152c |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-12-13T18:54:34Z |
| publishDate | 2020-11-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-e65bb6c2190a4d5587d430779050152c2022-12-21T23:34:51ZengPeytchinski PublishingJournal of IMAB1312-773X2020-11-012643469347410.5272/jimab.2020264.3469THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASEDesislava Marinova0https://orcid.org/0000-0003-0278-2977Maya Danovska1https://orcid.org/0000-0002-5945-2939Department Neurology and Neurosurgery, Faculty Medicine, Medical University, Pleven, Bulgaria.Department Neurology and Neurosurgery, Faculty Medicine, Medical University, Pleven, Bulgaria.Parkinson's disease (PD) is the second most common neurodegenerative disorder after the dementia of Alzheimer. The clinical presentation of PD is dominated by typical motor symptoms as resting tremor, cogwheel rigidity, bradykinesia, and postural instability. Non-motor symptoms (NMS) of Parkinson's disease are common but are often under-recognized in clinical practice either due to the lack of spontaneous complaints by the patients or to the absence of systematic questioning by healthcare professionals. In contrast to motor dysfunctions, non-motor symptoms frequently remain unreported. Recently, a self-completed NMS questionnaire and NMS scale for identification and evaluation of these symptoms have been validated. An international survey has shown that up to 62% of NMS in PD remain undeclared to healthcare professionals because patients are unaware that NMS symptoms are linked to PD. Based on both clinical and neuropathological data, PD, traditionally accepted as a dopaminergic motor disorder, now can be characterized as a multisystem neurodegenerative disease that involves many neurotransmitter systems and affects not only motor but non-motor functions, too.https://www.journal-imab-bg.org/issues-2020/issue4/2020vol26-issue4-3469-3474.pdfparkinson's disease (pd)non-motor symptoms (nms)quality of life |
| spellingShingle | Desislava Marinova Maya Danovska THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE Journal of IMAB parkinson's disease (pd) non-motor symptoms (nms) quality of life |
| title | THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE |
| title_full | THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE |
| title_fullStr | THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE |
| title_full_unstemmed | THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE |
| title_short | THE NON-MOTOR SYMPTOMS–CHALLENGE IN DIAGNOSIS OF PARKINSON'S DISEASE |
| title_sort | non motor symptoms challenge in diagnosis of parkinson s disease |
| topic | parkinson's disease (pd) non-motor symptoms (nms) quality of life |
| url | https://www.journal-imab-bg.org/issues-2020/issue4/2020vol26-issue4-3469-3474.pdf |
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