Valeric Acid Protects Dopaminergic Neurons by Suppressing Oxidative Stress, Neuroinflammation and Modulating Autophagy Pathways

Valeric Acid Protects Dopaminergic Neurons by Suppressing Oxidative Stress, Neuroinflammation and Modulating Autophagy Pathways

Parkinson’s disease, the second common neurodegenerative disease is clinically characterized by degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) with upregulation of neuroinflammatory markers and oxidative stress. Autophagy lysosome pathway (ALP) plays a major role i...

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Bibliographic Details
Main Authors: Richard L. Jayaraj, Rami Beiram, Sheikh Azimullah, Nagoor Meeran MF, Shreesh K. Ojha, Abdu Adem, Fakhreya Yousuf Jalal
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
valeric acid
rotenone
oxidative stress
neuroinflammation
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/21/20/7670

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