hESC‐Derived Epicardial Cells Promote Repair of Infarcted Hearts in Mouse and Swine

hESC‐Derived Epicardial Cells Promote Repair of Infarcted Hearts in Mouse and Swine

Abstract Myocardial infarction (MI) causes excessive damage to the myocardium, including the epicardium. However, whether pluripotent stem cell‐derived epicardial cells (EPs) can be a therapeutic approach for infarcted hearts remains unclear. Here, the authors report that intramyocardial injection o...

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Bibliographic Details
Main Authors: Xiao‐Ling Luo, Yun Jiang, Qiang Li, Xiu‐Jian Yu, Teng Ma, Hao Cao, Min‐Xia Ke, Peng Zhang, Ji‐Liang Tan, Yan‐Shan Gong, Li Wang, Ling Gao, Huang‐Tian Yang
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Advanced Science
Subjects:
hESC‐derived epicardial cells
inflammation
myocardial infarction
paracrine factor
type I interferon signaling
Online Access:https://doi.org/10.1002/advs.202300470

Internet

https://doi.org/10.1002/advs.202300470

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