Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis
Background/Aims Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade. Methods The cohort comprised 546 consecutive patients clinically diagnosed with...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Association for the Study of the Liver
2017-06-01
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| Series: | Clinical and Molecular Hepatology |
| Subjects: | |
| Online Access: | http://e-cmh.org/upload/pdf/cmh-2016-0055.pdf |
| _version_ | 1817983416961859584 |
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| author | Oidov Baatarkhuu Hye Won Lee Jacob George Dashchirev Munkh-Orshikh Baasankhuu Enkhtuvshin Sosorbaram Ariunaa Mohammed Eslam Sang Hoon Ahn Kwang-Hyub Han Do Young Kim |
| author_facet | Oidov Baatarkhuu Hye Won Lee Jacob George Dashchirev Munkh-Orshikh Baasankhuu Enkhtuvshin Sosorbaram Ariunaa Mohammed Eslam Sang Hoon Ahn Kwang-Hyub Han Do Young Kim |
| author_sort | Oidov Baatarkhuu |
| collection | DOAJ |
| description | Background/Aims Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade. Methods The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken. Results Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection. Conclusions Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country. |
| first_indexed | 2024-04-13T23:32:53Z |
| format | Article |
| id | doaj.art-e661bda4929a4109a0ac6bc486030288 |
| institution | Directory Open Access Journal |
| issn | 2287-2728 2287-285X |
| language | English |
| last_indexed | 2024-04-13T23:32:53Z |
| publishDate | 2017-06-01 |
| publisher | Korean Association for the Study of the Liver |
| record_format | Article |
| series | Clinical and Molecular Hepatology |
| spelling | doaj.art-e661bda4929a4109a0ac6bc4860302882022-12-22T02:24:50ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2017-06-0123214715310.3350/cmh.2016.00551352Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysisOidov Baatarkhuu0Hye Won Lee1Jacob George2Dashchirev Munkh-Orshikh3Baasankhuu Enkhtuvshin4Sosorbaram Ariunaa5Mohammed Eslam6Sang Hoon Ahn7Kwang-Hyub Han8Do Young Kim9 Department of Infectious Diseases, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Storr Liver Unit, Westmead Millennium Institute and Westmead Hospital, University of Sydney, NSW, Australia Department of Infectious Diseases, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia Department of Infectious Diseases, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia National Center for Communicable Diseases, Ulaanbaatar, Mongolia Storr Liver Unit, Westmead Millennium Institute and Westmead Hospital, University of Sydney, NSW, Australia Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaBackground/Aims Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade. Methods The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken. Results Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection. Conclusions Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.http://e-cmh.org/upload/pdf/cmh-2016-0055.pdfAcute hepatitisHepatitis AHepatitis BHepatitis CHepatitis D |
| spellingShingle | Oidov Baatarkhuu Hye Won Lee Jacob George Dashchirev Munkh-Orshikh Baasankhuu Enkhtuvshin Sosorbaram Ariunaa Mohammed Eslam Sang Hoon Ahn Kwang-Hyub Han Do Young Kim Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis Clinical and Molecular Hepatology Acute hepatitis Hepatitis A Hepatitis B Hepatitis C Hepatitis D |
| title | Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis |
| title_full | Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis |
| title_fullStr | Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis |
| title_full_unstemmed | Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis |
| title_short | Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis |
| title_sort | acute hepatitis a b and c but not d is still prevalent in mongolia a time trend analysis |
| topic | Acute hepatitis Hepatitis A Hepatitis B Hepatitis C Hepatitis D |
| url | http://e-cmh.org/upload/pdf/cmh-2016-0055.pdf |
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