Micronutrient's deficiency in India: a systematic review and meta-analysis
India is coming to grips with a stage of nutrition transition. According to the Food Safety and Standards Authority of India (FSSAI), preventable micronutrient deficiency is arising public health precedence in India. However, the foremost public health concern is the lack of national prevalence data...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2021-01-01
|
| Series: | Journal of Nutritional Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2048679021001026/type/journal_article |
| _version_ | 1811155952771006464 |
|---|---|
| author | U. Venkatesh Akash Sharma Velmurugan A. Ananthan Padmavathi Subbiah R. Durga CSIR Summer Research training team |
| author_facet | U. Venkatesh Akash Sharma Velmurugan A. Ananthan Padmavathi Subbiah R. Durga CSIR Summer Research training team |
| author_sort | U. Venkatesh |
| collection | DOAJ |
| description | India is coming to grips with a stage of nutrition transition. According to the Food Safety and Standards Authority of India (FSSAI), preventable micronutrient deficiency is arising public health precedence in India. However, the foremost public health concern is the lack of national prevalence data. The present study was carried out to estimate the pooled age-wise prevalence of six preventable micronutrient deficiencies (vitamin A, vitamin B12, vitamin D, iron, iodine and folic acid) in India. A systematic review was carried out on PubMed and Global Index Medicus databases using the Boolean search strategy. Statistical analyses were done using R software, version 3.6. 2. PRISMA guidelines were strictly adhered to during the review. A preliminary literature search yielded 4302 articles; however, 270 original research articles were found eligible to be included in quantitative synthesis. The estimated overall prevalence was 17 % [95 % confidence interval (CI) 0⋅07, 0⋅26] for iodine deficiency, 37 % (95 % CI 0⋅27, 0⋅46) for folic acid deficiency, 54 % (95 % CI 0⋅49, 0⋅59) for iron deficiency, 53 % (95 % CI 0⋅41, 0⋅64) for vitamin B12 deficiency, 19 % (95 % CI 0⋅09, 0⋅29) for vitamin A deficiency and 61 % (95 % CI 0⋅07, 0⋅26) for vitamin D with high heterogeneity. We classified the population into infants (0–5 years), adolescents (<18 years), adults (>18 years) and pregnant women. Iron deficiency was most prevalent (61 %) in pregnant women. The results of the present study reinforce the data on micronutrient deficiency in India and warrant the immediate need for further active public health interventions to address these deficiencies. The study is registered with PROSPERO (CRD42020205043). |
| first_indexed | 2024-04-10T04:43:27Z |
| format | Article |
| id | doaj.art-e6630735de4341e09bfbef92406e0582 |
| institution | Directory Open Access Journal |
| issn | 2048-6790 |
| language | English |
| last_indexed | 2024-04-10T04:43:27Z |
| publishDate | 2021-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Nutritional Science |
| spelling | doaj.art-e6630735de4341e09bfbef92406e05822023-03-09T12:38:45ZengCambridge University PressJournal of Nutritional Science2048-67902021-01-011010.1017/jns.2021.102Micronutrient's deficiency in India: a systematic review and meta-analysisU. Venkatesh0https://orcid.org/0000-0001-8059-9364Akash Sharma1https://orcid.org/0000-0002-6822-4946Velmurugan A. Ananthan2https://orcid.org/0000-0003-2977-8484Padmavathi Subbiah3R. Durga4CSIR Summer Research training team5Department of Community Medicine & Family Medicine, All India Institute of Medical Sciences, Gorakhpur, IndiaRush University Medical Center, Chicago, IL, USADepartment of Community Medicine, Government Theni Medical College, Theni, Tamil Nadu, IndiaModel Rural Health Research Unit, ICMR-NIE, Kallur, Tirunelveli, Tamil Nadu, IndiaDepartment of Paediatric and Preventive Dentistry, Faculty of Dental Sciences, King George Medical University, Lucknow, IndiaDepartment of Community Medicine & Family Medicine, All India Institute of Medical Sciences, Gorakhpur, IndiaIndia is coming to grips with a stage of nutrition transition. According to the Food Safety and Standards Authority of India (FSSAI), preventable micronutrient deficiency is arising public health precedence in India. However, the foremost public health concern is the lack of national prevalence data. The present study was carried out to estimate the pooled age-wise prevalence of six preventable micronutrient deficiencies (vitamin A, vitamin B12, vitamin D, iron, iodine and folic acid) in India. A systematic review was carried out on PubMed and Global Index Medicus databases using the Boolean search strategy. Statistical analyses were done using R software, version 3.6. 2. PRISMA guidelines were strictly adhered to during the review. A preliminary literature search yielded 4302 articles; however, 270 original research articles were found eligible to be included in quantitative synthesis. The estimated overall prevalence was 17 % [95 % confidence interval (CI) 0⋅07, 0⋅26] for iodine deficiency, 37 % (95 % CI 0⋅27, 0⋅46) for folic acid deficiency, 54 % (95 % CI 0⋅49, 0⋅59) for iron deficiency, 53 % (95 % CI 0⋅41, 0⋅64) for vitamin B12 deficiency, 19 % (95 % CI 0⋅09, 0⋅29) for vitamin A deficiency and 61 % (95 % CI 0⋅07, 0⋅26) for vitamin D with high heterogeneity. We classified the population into infants (0–5 years), adolescents (<18 years), adults (>18 years) and pregnant women. Iron deficiency was most prevalent (61 %) in pregnant women. The results of the present study reinforce the data on micronutrient deficiency in India and warrant the immediate need for further active public health interventions to address these deficiencies. The study is registered with PROSPERO (CRD42020205043).https://www.cambridge.org/core/product/identifier/S2048679021001026/type/journal_articleIodine deficiencyIron deficiencyMeta-analysisMicronutrient deficiencyVitamin A deficiencyVitamin B12 deficiencyVitamin D deficiency |
| spellingShingle | U. Venkatesh Akash Sharma Velmurugan A. Ananthan Padmavathi Subbiah R. Durga CSIR Summer Research training team Micronutrient's deficiency in India: a systematic review and meta-analysis Journal of Nutritional Science Iodine deficiency Iron deficiency Meta-analysis Micronutrient deficiency Vitamin A deficiency Vitamin B12 deficiency Vitamin D deficiency |
| title | Micronutrient's deficiency in India: a systematic review and meta-analysis |
| title_full | Micronutrient's deficiency in India: a systematic review and meta-analysis |
| title_fullStr | Micronutrient's deficiency in India: a systematic review and meta-analysis |
| title_full_unstemmed | Micronutrient's deficiency in India: a systematic review and meta-analysis |
| title_short | Micronutrient's deficiency in India: a systematic review and meta-analysis |
| title_sort | micronutrient s deficiency in india a systematic review and meta analysis |
| topic | Iodine deficiency Iron deficiency Meta-analysis Micronutrient deficiency Vitamin A deficiency Vitamin B12 deficiency Vitamin D deficiency |
| url | https://www.cambridge.org/core/product/identifier/S2048679021001026/type/journal_article |
| work_keys_str_mv | AT uvenkatesh micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis AT akashsharma micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis AT velmuruganaananthan micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis AT padmavathisubbiah micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis AT rdurga micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis AT csirsummerresearchtrainingteam micronutrientsdeficiencyinindiaasystematicreviewandmetaanalysis |