Circadian light-input pathways in Drosophila
Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied. The Drosophila brain contains approximately 150 neurons that rhythmically express circadian cl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2016-01-01
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| Series: | Communicative & Integrative Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/19420889.2015.1102805 |
| _version_ | 1818577750522331136 |
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| author | Taishi Yoshii Christiane Hermann-Luibl Charlotte Helfrich-Förster |
| author_facet | Taishi Yoshii Christiane Hermann-Luibl Charlotte Helfrich-Förster |
| author_sort | Taishi Yoshii |
| collection | DOAJ |
| description | Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied. The Drosophila brain contains approximately 150 neurons that rhythmically express circadian clock genes. These neurons are called “clock neurons” and control behavioral activity rhythms. Many clock neurons express the Cryptochrome (CRY) protein, which is sensitive to UV and blue light, and thus enables clock neurons deep in the brain to directly perceive light. In addition to the CRY protein, external photoreceptors in the Drosophila eyes play an important role in circadian light-input pathways. Recent studies have provided new insights into the mechanisms that integrate these light inputs into the circadian network of the brain. In this review, we will summarize the current knowledge on the light entrainment pathways in the Drosophila circadian clock. |
| first_indexed | 2024-12-16T06:34:53Z |
| format | Article |
| id | doaj.art-e66576fb062c4be5ad59cad4a66a3e11 |
| institution | Directory Open Access Journal |
| issn | 1942-0889 |
| language | English |
| last_indexed | 2024-12-16T06:34:53Z |
| publishDate | 2016-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Communicative & Integrative Biology |
| spelling | doaj.art-e66576fb062c4be5ad59cad4a66a3e112022-12-21T22:40:48ZengTaylor & Francis GroupCommunicative & Integrative Biology1942-08892016-01-019110.1080/19420889.2015.11028051102805Circadian light-input pathways in DrosophilaTaishi Yoshii0Christiane Hermann-Luibl1Charlotte Helfrich-Förster2Graduate School of Natural Science and Technology, Okayama UniversityNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of WürzburgNeurobiology and Genetics, Theodor-Boveri Institute, Biocenter, University of WürzburgLight is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied. The Drosophila brain contains approximately 150 neurons that rhythmically express circadian clock genes. These neurons are called “clock neurons” and control behavioral activity rhythms. Many clock neurons express the Cryptochrome (CRY) protein, which is sensitive to UV and blue light, and thus enables clock neurons deep in the brain to directly perceive light. In addition to the CRY protein, external photoreceptors in the Drosophila eyes play an important role in circadian light-input pathways. Recent studies have provided new insights into the mechanisms that integrate these light inputs into the circadian network of the brain. In this review, we will summarize the current knowledge on the light entrainment pathways in the Drosophila circadian clock.http://dx.doi.org/10.1080/19420889.2015.1102805circadian clockcircadian rhythmcryptochromeDrosophila melanogasterlight entrainmentphotoreceptorpigment-dispersing factor |
| spellingShingle | Taishi Yoshii Christiane Hermann-Luibl Charlotte Helfrich-Förster Circadian light-input pathways in Drosophila Communicative & Integrative Biology circadian clock circadian rhythm cryptochrome Drosophila melanogaster light entrainment photoreceptor pigment-dispersing factor |
| title | Circadian light-input pathways in Drosophila |
| title_full | Circadian light-input pathways in Drosophila |
| title_fullStr | Circadian light-input pathways in Drosophila |
| title_full_unstemmed | Circadian light-input pathways in Drosophila |
| title_short | Circadian light-input pathways in Drosophila |
| title_sort | circadian light input pathways in drosophila |
| topic | circadian clock circadian rhythm cryptochrome Drosophila melanogaster light entrainment photoreceptor pigment-dispersing factor |
| url | http://dx.doi.org/10.1080/19420889.2015.1102805 |
| work_keys_str_mv | AT taishiyoshii circadianlightinputpathwaysindrosophila AT christianehermannluibl circadianlightinputpathwaysindrosophila AT charlottehelfrichforster circadianlightinputpathwaysindrosophila |