Impact of Cytochrome P450 Enzymes on the Phase I Metabolism of Drugs

Impact of Cytochrome P450 Enzymes on the Phase I Metabolism of Drugs

The cytochrome P450 (CYP) enzyme family is the major enzyme system catalyzing the phase I metabolism of xenobiotics, including pharmaceuticals and toxic compounds in the environment. A major part of the CYP-dependent xenobiotic metabolism is due to polymorphic and inducible enzymes, which may, quant...

Full description

Bibliographic Details
Main Authors: Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Elisabetta Scali, Domenica Scumaci, Michele Pellegrino, Stefano Aquaro, Carmela Saturnino, Maria Stefania Sinicropi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Applied Sciences
Subjects:
metabolites
hydroxylation
monooxygenases
CYP450
hydroxylated metabolites
Online Access:https://www.mdpi.com/2076-3417/13/10/6045

Internet

https://www.mdpi.com/2076-3417/13/10/6045

Similar Items