Biosynthesis of fragin is controlled by a novel quorum sensing signal
Fragin is a diazeniumdiolate metabolite with antifungal activity, produced by some bacteria. Here, Jenul et al. show that metal chelation is the molecular basis of fragin’s antifungal activity, and that a gene cluster directing fragin biosynthesis is also involved in the synthesis of a signal molecu...
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Bibliographic Details
| Main Authors: |
Christian Jenul,
Simon Sieber,
Christophe Daeppen,
Anugraha Mathew,
Martina Lardi,
Gabriella Pessi,
Dominic Hoepfner,
Markus Neuburger,
Anthony Linden,
Karl Gademann,
Leo Eberl |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-03690-2
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