The benefits of using selenium in the treatment of Chagas disease: prevention of right ventricle chamber dilatation and reversion of Trypanosoma cruzi-induced acute and chronic cardiomyopathy in mice

The benefits of using selenium in the treatment of Chagas disease: prevention of right ventricle chamber dilatation and reversion of Trypanosoma cruzi-induced acute and chronic cardiomyopathy in mice

Cardiac damage is a frequent manifestation of Chagas disease, which is caused by the parasite Trypanosoma cruzi. Selenium (Se) is an essential micronutrient, the deficiency of which has been implicated in the development of cardiomyopathy. Our group has previously demonstrated that Se supplementatio...

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Bibliographic Details
Main Authors: Andréa P de Souza, Linda A Jelicks, Herbert B Tanowitz, Bianca P Olivieri, Monica M Medeiros, Gabriel M Oliveira, Andrea Rodrigues Cordovil Pires, Alessandro M dos Santos, Tania C Araújo-Jorge
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2010-09-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
selenium
cardiomyopathy
Chagas disease
Trypanosoma cruzi
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762010000600003&lng=en&tlng=en

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