A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report

Abstract Background Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disorder characterized by regional lymphadenopathy. Clinical symptoms range from mild fever and tenderness to upper respiratory syndrome. A few cases have been observed during pregnancy or Hashimoto's disease. What we...

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Main Authors: Bashar Bazkke, Joli Osman, Mohammad Shahrour, Mohammad Ziadeh, Aya Haji Mohamad, Mohamed Imad Eddin Mouhandes, Ammar Niazi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Thyroid Research
Subjects:
Online Access:https://doi.org/10.1186/s13044-022-00135-3
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author Bashar Bazkke
Joli Osman
Mohammad Shahrour
Mohammad Ziadeh
Aya Haji Mohamad
Mohamed Imad Eddin Mouhandes
Ammar Niazi
author_facet Bashar Bazkke
Joli Osman
Mohammad Shahrour
Mohammad Ziadeh
Aya Haji Mohamad
Mohamed Imad Eddin Mouhandes
Ammar Niazi
author_sort Bashar Bazkke
collection DOAJ
description Abstract Background Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disorder characterized by regional lymphadenopathy. Clinical symptoms range from mild fever and tenderness to upper respiratory syndrome. A few cases have been observed during pregnancy or Hashimoto's disease. What we describe here is the first observed case of KFD in a pregnant woman with a history of Hashimoto's thyroiditis. Case presentation A 36-year-old woman presented to Aleppo University Hospital during the 13th week of gestation with a painful cervical node on the right side of her neck. The patient's previous medical history confirmed Hashimoto's thyroiditis for several years. After histopathological examinations and radiological investigations, she was diagnosed with Kikuchi-Fujimoto disease and treated with corticosteroids. Although the patient did not adhere to the treatment very well due to her concerns for the fetus, the clinical picture improved after delivery. The patient now is on follow-up and continuing the current treatment with corticosteroids. Conclusions Further investigations need to be conducted to understand the possible autoimmune etiology of KFD when it is associated with Hashimoto's thyroiditis disease. It is also necessary to understand the relationship between this disease and pregnancy.
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spelling doaj.art-e66a651a640e4b8a8112c52a138868712023-03-22T10:36:00ZengBMCThyroid Research1756-66142022-09-011511410.1186/s13044-022-00135-3A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case reportBashar Bazkke0Joli Osman1Mohammad Shahrour2Mohammad Ziadeh3Aya Haji Mohamad4Mohamed Imad Eddin Mouhandes5Ammar Niazi6Faculty of Medicine, University of AleppoFaculty of Medicine, University of AleppoFaculty of Medicine, University of AleppoFaculty of Medicine, University of AleppoFaculty of Medicine, University of AleppoDepartment of Pathology, Faculty of Medicine, University of AleppoDepartment of General Surgery, Faculty of Medicine, Aleppo University HospitalAbstract Background Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disorder characterized by regional lymphadenopathy. Clinical symptoms range from mild fever and tenderness to upper respiratory syndrome. A few cases have been observed during pregnancy or Hashimoto's disease. What we describe here is the first observed case of KFD in a pregnant woman with a history of Hashimoto's thyroiditis. Case presentation A 36-year-old woman presented to Aleppo University Hospital during the 13th week of gestation with a painful cervical node on the right side of her neck. The patient's previous medical history confirmed Hashimoto's thyroiditis for several years. After histopathological examinations and radiological investigations, she was diagnosed with Kikuchi-Fujimoto disease and treated with corticosteroids. Although the patient did not adhere to the treatment very well due to her concerns for the fetus, the clinical picture improved after delivery. The patient now is on follow-up and continuing the current treatment with corticosteroids. Conclusions Further investigations need to be conducted to understand the possible autoimmune etiology of KFD when it is associated with Hashimoto's thyroiditis disease. It is also necessary to understand the relationship between this disease and pregnancy.https://doi.org/10.1186/s13044-022-00135-3Kikuchi-Fujimoto diseaseLymphadenitisLymphadenopathyHashimoto's ThyroiditisPregnancy
spellingShingle Bashar Bazkke
Joli Osman
Mohammad Shahrour
Mohammad Ziadeh
Aya Haji Mohamad
Mohamed Imad Eddin Mouhandes
Ammar Niazi
A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
Thyroid Research
Kikuchi-Fujimoto disease
Lymphadenitis
Lymphadenopathy
Hashimoto's Thyroiditis
Pregnancy
title A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
title_full A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
title_fullStr A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
title_full_unstemmed A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
title_short A pregnant women with history of hashimoto's thyroiditis diagnosed with Kikuchi-Fujimoto disease: the first case report
title_sort pregnant women with history of hashimoto s thyroiditis diagnosed with kikuchi fujimoto disease the first case report
topic Kikuchi-Fujimoto disease
Lymphadenitis
Lymphadenopathy
Hashimoto's Thyroiditis
Pregnancy
url https://doi.org/10.1186/s13044-022-00135-3
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