DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion

DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion

Vidya Chidambaran,1,2 Xue Zhang,3,4 Lisa J Martin,2,3 Lili Ding,5 Matthew T Weirauch,6–8 Kristie Geisler,1 Bobbie L Stubbeman,1 Senthilkumar Sadhasivam,1,2 Hong Ji4,9 1Department of Anesthesiology, 2Department of Pediatrics, 3Division of Human Genetics, 4Pyrosequencing Core for Genomic and...

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Bibliographic Details
Main Authors: Chidambaran V, Zhang X, Martin LJ, Ding L, Weirauch MT, Geisler K, Stubbeman BL, Sadhasivam S, Ji H
Format: Article
Language:English
Published: Dove Medical Press 2017-05-01
Series:Pharmacogenomics and Personalized Medicine
Subjects:
OPRM1
epigenetics
pain
chronic postsurgical pain
DNA methylation
Online Access:https://www.dovepress.com/dna-methylation-at-the-mu-1-opioid-receptor-gene-oprm1-promoter-predic-peer-reviewed-article-PGPM

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