WTAP-mediated m6A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis
Abstract An imbalance in the differentiation potential of bone marrow mesenchymal stem cells (BMSCs) is an important pathogenic mechanism underlying osteoporosis (OP). N6-methyladenosine (m6A) is the most common post-transcriptional modification in eukaryotic cells. The role of the Wilms’ tumor 1-as...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-01-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05565-x |