Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options

<div> <b>Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options</b> </div> <div> <b><br> </b> </div> Yu.E. Dobrokhotova<sup>1</sup>, L.V. Saprykina<sup>1&l...

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Main Authors: Yu.E. Dobrokhotova, Saprykina L.V., Saprykina O.A.
Format: Article
Language:Russian
Published: LCC «Medicine-Inform» 2018-09-01
Series:РМЖ. Мать и дитя
Online Access:http://wchjournal.com/upload/iblock/d86/d86e84b56e6a77c10478d35f19e8ed62.pdf
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author Yu.E. Dobrokhotova
Saprykina L.V.
Saprykina O.A.
author_facet Yu.E. Dobrokhotova
Saprykina L.V.
Saprykina O.A.
author_sort Yu.E. Dobrokhotova
collection DOAJ
description <div> <b>Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options</b> </div> <div> <b><br> </b> </div> Yu.E. Dobrokhotova<sup>1</sup>, L.V. Saprykina<sup>1</sup>, O.A. Saprykina<sup>2</sup><br> <sup>1</sup> Pirogov Russian National Research Medical University, Moscow, Russian Federation<br> <sup>2</sup> Medical center “Vrachevatel”, Moscow reg., Pushkino, Russian Federation<br> <br> Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV (Papillomaviridae family) is a non-enveloped virus, which contains a double-stranded DNA and induces lesions of the skin and mucous membranes. The clinical manifestations of НPV-infection depend on multiple factors including the viral genotype, the genotype of the host, the type of epithelium infected and environmental factors such as the status of host immunity and nutritional factors. Primary prevention of HPV infection is possible with the help of vaccination against HPV, but the level of vaccination in a number of countries, including Russia, remains low. Depending on the manifestations of papillomavirus infection on the genitals, latent, subclinical and clinical forms are distinguished. Anogenital warts (AW) are the most common form of HPV-infections. AW are benign proliferative lesions caused by HPV types 6 and 11. Diagnostics of AW is usually based on clinical data. During pregnancy, active proliferation of the AW is possible. The purpose of AW therapy is lesions destruction. Chemical, cytotoxic and physical methods of AW destruction are applied. Methods of AW destruction are chemical methods, cytotoxic methods, physical methods. Local therapy with activated glycyrrhizic acid for pre- and postoperative preparation is warranted.<br> <br> <b>Key words:</b> human papillomavirus, HPV, condyloma acuminatum, anogenital warts, treatment, destruction, diagnosis, pregnancy, activated glycyrrhizic acid, antiviral and immunostimulatory activity.<br> <b>For citation: </b>Dobrokhotova Yu.E., Saprykina L.V., Saprykina O.A. Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options. Russian journal of Woman and Child Health. 2018;1(1):57–61.<br>
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spelling doaj.art-e66d0cc5b6004d78a93e77a99d1dfdba2024-02-26T10:13:31ZrusLCC «Medicine-Inform»РМЖ. Мать и дитя2618-84302686-71842018-09-011132177Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment optionsYu.E. Dobrokhotova0Saprykina L.V.1Saprykina O.A.2Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Woman and Child Health, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<div> <b>Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options</b> </div> <div> <b><br> </b> </div> Yu.E. Dobrokhotova<sup>1</sup>, L.V. Saprykina<sup>1</sup>, O.A. Saprykina<sup>2</sup><br> <sup>1</sup> Pirogov Russian National Research Medical University, Moscow, Russian Federation<br> <sup>2</sup> Medical center “Vrachevatel”, Moscow reg., Pushkino, Russian Federation<br> <br> Human papillomavirus (HPV) is the most common sexually transmitted infection. HPV (Papillomaviridae family) is a non-enveloped virus, which contains a double-stranded DNA and induces lesions of the skin and mucous membranes. The clinical manifestations of НPV-infection depend on multiple factors including the viral genotype, the genotype of the host, the type of epithelium infected and environmental factors such as the status of host immunity and nutritional factors. Primary prevention of HPV infection is possible with the help of vaccination against HPV, but the level of vaccination in a number of countries, including Russia, remains low. Depending on the manifestations of papillomavirus infection on the genitals, latent, subclinical and clinical forms are distinguished. Anogenital warts (AW) are the most common form of HPV-infections. AW are benign proliferative lesions caused by HPV types 6 and 11. Diagnostics of AW is usually based on clinical data. During pregnancy, active proliferation of the AW is possible. The purpose of AW therapy is lesions destruction. Chemical, cytotoxic and physical methods of AW destruction are applied. Methods of AW destruction are chemical methods, cytotoxic methods, physical methods. Local therapy with activated glycyrrhizic acid for pre- and postoperative preparation is warranted.<br> <br> <b>Key words:</b> human papillomavirus, HPV, condyloma acuminatum, anogenital warts, treatment, destruction, diagnosis, pregnancy, activated glycyrrhizic acid, antiviral and immunostimulatory activity.<br> <b>For citation: </b>Dobrokhotova Yu.E., Saprykina L.V., Saprykina O.A. Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options. Russian journal of Woman and Child Health. 2018;1(1):57–61.<br>http://wchjournal.com/upload/iblock/d86/d86e84b56e6a77c10478d35f19e8ed62.pdf
spellingShingle Yu.E. Dobrokhotova
Saprykina L.V.
Saprykina O.A.
Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
РМЖ. Мать и дитя
title Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
title_full Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
title_fullStr Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
title_full_unstemmed Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
title_short Lesions of skin and mucous membranes of female genital organs associated with human papillomavirus. Local treatment options
title_sort lesions of skin and mucous membranes of female genital organs associated with human papillomavirus local treatment options
url http://wchjournal.com/upload/iblock/d86/d86e84b56e6a77c10478d35f19e8ed62.pdf
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