The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data

(1) Background: Hip degenerative disorder is a common geriatric disease is the main causes to lead to total hip replacement (THR). The surgical timing of THR is crucial for post-operative recovery. Deep learning (DL) algorithms can be used to detect anomalies in medical images and predict the need f...

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Main Authors: Chih-Chi Chen, Jen-Fu Huang, Wei-Cheng Lin, Chi-Tung Cheng, Shann-Ching Chen, Chih-Yuan Fu, Mel S. Lee, Chien-Hung Liao, Chia-Ying Chung
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/4/458
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author Chih-Chi Chen
Jen-Fu Huang
Wei-Cheng Lin
Chi-Tung Cheng
Shann-Ching Chen
Chih-Yuan Fu
Mel S. Lee
Chien-Hung Liao
Chia-Ying Chung
author_facet Chih-Chi Chen
Jen-Fu Huang
Wei-Cheng Lin
Chi-Tung Cheng
Shann-Ching Chen
Chih-Yuan Fu
Mel S. Lee
Chien-Hung Liao
Chia-Ying Chung
author_sort Chih-Chi Chen
collection DOAJ
description (1) Background: Hip degenerative disorder is a common geriatric disease is the main causes to lead to total hip replacement (THR). The surgical timing of THR is crucial for post-operative recovery. Deep learning (DL) algorithms can be used to detect anomalies in medical images and predict the need for THR. The real world data (RWD) were used to validate the artificial intelligence and DL algorithm in medicine but there was no previous study to prove its function in THR prediction. (2) Methods: We designed a sequential two-stage hip replacement prediction deep learning algorithm to identify the possibility of THR in three months of hip joints by plain pelvic radiography (PXR). We also collected RWD to validate the performance of this algorithm. (3) Results: The RWD totally included 3766 PXRs from 2018 to 2019. The overall accuracy of the algorithm was 0.9633; sensitivity was 0.9450; specificity was 1.000 and the precision was 1.000. The negative predictive value was 0.9009, the false negative rate was 0.0550, and the F1 score was 0.9717. The area under curve was 0.972 with 95% confidence interval from 0.953 to 0.987. (4) Conclusions: In summary, this DL algorithm can provide an accurate and reliable method for detecting hip degeneration and predicting the need for further THR. RWD offered an alternative support of the algorithm and validated its function to save time and cost.
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spelling doaj.art-e66d8beb79184f89ab59c44aa8a159ab2023-11-17T18:22:22ZengMDPI AGBioengineering2306-53542023-04-0110445810.3390/bioengineering10040458The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World DataChih-Chi Chen0Jen-Fu Huang1Wei-Cheng Lin2Chi-Tung Cheng3Shann-Ching Chen4Chih-Yuan Fu5Mel S. Lee6Chien-Hung Liao7Chia-Ying Chung8Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Orthopaedic Surgery, Pao-Chien Hospital, Pingtung 90078, TaiwanDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, TaiwanDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taoyuan 33328, Taiwan(1) Background: Hip degenerative disorder is a common geriatric disease is the main causes to lead to total hip replacement (THR). The surgical timing of THR is crucial for post-operative recovery. Deep learning (DL) algorithms can be used to detect anomalies in medical images and predict the need for THR. The real world data (RWD) were used to validate the artificial intelligence and DL algorithm in medicine but there was no previous study to prove its function in THR prediction. (2) Methods: We designed a sequential two-stage hip replacement prediction deep learning algorithm to identify the possibility of THR in three months of hip joints by plain pelvic radiography (PXR). We also collected RWD to validate the performance of this algorithm. (3) Results: The RWD totally included 3766 PXRs from 2018 to 2019. The overall accuracy of the algorithm was 0.9633; sensitivity was 0.9450; specificity was 1.000 and the precision was 1.000. The negative predictive value was 0.9009, the false negative rate was 0.0550, and the F1 score was 0.9717. The area under curve was 0.972 with 95% confidence interval from 0.953 to 0.987. (4) Conclusions: In summary, this DL algorithm can provide an accurate and reliable method for detecting hip degeneration and predicting the need for further THR. RWD offered an alternative support of the algorithm and validated its function to save time and cost.https://www.mdpi.com/2306-5354/10/4/458total hip replacementdeep learningartificial intelligencereal world data
spellingShingle Chih-Chi Chen
Jen-Fu Huang
Wei-Cheng Lin
Chi-Tung Cheng
Shann-Ching Chen
Chih-Yuan Fu
Mel S. Lee
Chien-Hung Liao
Chia-Ying Chung
The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
Bioengineering
total hip replacement
deep learning
artificial intelligence
real world data
title The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
title_full The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
title_fullStr The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
title_full_unstemmed The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
title_short The Feasibility and Performance of Total Hip Replacement Prediction Deep Learning Algorithm with Real World Data
title_sort feasibility and performance of total hip replacement prediction deep learning algorithm with real world data
topic total hip replacement
deep learning
artificial intelligence
real world data
url https://www.mdpi.com/2306-5354/10/4/458
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