Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China
Abstract The current study aimed to assess the dietary salt intake in patients with CKD in Jiangsu province and investigate the relationship of urinary sodium excretion with blood pressure. A total of 800 patients with CKD stages 1–4 were recruited. All enrolled patients were asked to collect comple...
| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Wiley
2021-07-01
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| Collection: | The Journal of Clinical Hypertension |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1111/jch.14307 |
| _version_ | 1827778919539933184 |
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| author | Lianqin Sun Suyan Duan Chenyan Zuo Zhiying Sun Guangyan Nie Chengning Zhang Ming Zeng Bin Sun Yanggang Yuan Ningning Wang Huijuan Mao Changying Xing Bo Zhang |
| author_facet | Lianqin Sun Suyan Duan Chenyan Zuo Zhiying Sun Guangyan Nie Chengning Zhang Ming Zeng Bin Sun Yanggang Yuan Ningning Wang Huijuan Mao Changying Xing Bo Zhang |
| author_sort | Lianqin Sun |
| collection | DOAJ |
| description | Abstract The current study aimed to assess the dietary salt intake in patients with CKD in Jiangsu province and investigate the relationship of urinary sodium excretion with blood pressure. A total of 800 patients with CKD stages 1–4 were recruited. All enrolled patients were asked to collect complete 24‐h urine specimen. At the same time, patient's demographic and laboratory data were recorded. The mean age was 47.45 ± 15.25 years old, including 423 men and 377 women. There was no significant difference in urinary sodium excretion among different stages of CKD (p = .748). This study revealed that the median urinary sodium excretion of all patients was 127.20 mmol/d (IQR 91.03–172.06), corresponding to a salt intake of 7.4 g/d. Among them, only 167 (20.9%) cases had salt intake <5 g/d. Moreover, urinary sodium excretion in overweight group and obese group was higher than that in normal weight group (p = .001, p ˂ .001). Likewise, urinary sodium excretion in men was higher than that in women (p ˂ .001). Spearman correlation analysis indicated that urinary sodium excretion positively correlated with urinary protein excretion (r = .178, p ˂ .001), SBP (r = .109, p = .002), and DBP (r = .086, p = .015). After adjusting for age, gender, BMI, eGFR, urinary protein excretion, and history of taking antihypertensive drug, multivariate linear regression demonstrated that higher level of urinary sodium excretion associated with increased level of SBP, DBP, and MAP (β = 0.020, p = .049; β = 0.015, p = .040; β = 0.016, p = .025, respectively). In conclusion, the dietary salt intake in CKD patients, especially in male, overweight and obese subjects, remains high in Jiangsu province. It is vital to decline salt intake to control blood pressure in Jiangsu patients with CKD. |
| first_indexed | 2024-03-11T14:42:53Z |
| format | Article |
| id | doaj.art-e66d94e0109948a6b3cb1535862bb041 |
| institution | Directory Open Access Journal |
| issn | 1524-6175 1751-7176 |
| language | English |
| last_indexed | 2024-03-11T14:42:53Z |
| publishDate | 2021-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Journal of Clinical Hypertension |
| spelling | doaj.art-e66d94e0109948a6b3cb1535862bb0412023-10-30T13:30:36ZengWileyThe Journal of Clinical Hypertension1524-61751751-71762021-07-012371372137910.1111/jch.14307Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, ChinaLianqin Sun0Suyan Duan1Chenyan Zuo2Zhiying Sun3Guangyan Nie4Chengning Zhang5Ming Zeng6Bin Sun7Yanggang Yuan8Ningning Wang9Huijuan Mao10Changying Xing11Bo Zhang12Department of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Gastroenterology Lianyungang No 1 People's Hospital Lianyungang ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaDepartment of Nephrology Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University Nanjing Medical University Nanjing ChinaAbstract The current study aimed to assess the dietary salt intake in patients with CKD in Jiangsu province and investigate the relationship of urinary sodium excretion with blood pressure. A total of 800 patients with CKD stages 1–4 were recruited. All enrolled patients were asked to collect complete 24‐h urine specimen. At the same time, patient's demographic and laboratory data were recorded. The mean age was 47.45 ± 15.25 years old, including 423 men and 377 women. There was no significant difference in urinary sodium excretion among different stages of CKD (p = .748). This study revealed that the median urinary sodium excretion of all patients was 127.20 mmol/d (IQR 91.03–172.06), corresponding to a salt intake of 7.4 g/d. Among them, only 167 (20.9%) cases had salt intake <5 g/d. Moreover, urinary sodium excretion in overweight group and obese group was higher than that in normal weight group (p = .001, p ˂ .001). Likewise, urinary sodium excretion in men was higher than that in women (p ˂ .001). Spearman correlation analysis indicated that urinary sodium excretion positively correlated with urinary protein excretion (r = .178, p ˂ .001), SBP (r = .109, p = .002), and DBP (r = .086, p = .015). After adjusting for age, gender, BMI, eGFR, urinary protein excretion, and history of taking antihypertensive drug, multivariate linear regression demonstrated that higher level of urinary sodium excretion associated with increased level of SBP, DBP, and MAP (β = 0.020, p = .049; β = 0.015, p = .040; β = 0.016, p = .025, respectively). In conclusion, the dietary salt intake in CKD patients, especially in male, overweight and obese subjects, remains high in Jiangsu province. It is vital to decline salt intake to control blood pressure in Jiangsu patients with CKD.https://doi.org/10.1111/jch.14307blood pressurechronic kidney diseasesalt intakeurinary sodium excretion |
| spellingShingle | Lianqin Sun Suyan Duan Chenyan Zuo Zhiying Sun Guangyan Nie Chengning Zhang Ming Zeng Bin Sun Yanggang Yuan Ningning Wang Huijuan Mao Changying Xing Bo Zhang Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China The Journal of Clinical Hypertension blood pressure chronic kidney disease salt intake urinary sodium excretion |
| title | Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China |
| title_full | Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China |
| title_fullStr | Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China |
| title_full_unstemmed | Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China |
| title_short | Characteristics of urinary sodium excretion in patients with chronic kidney disease in Jiangsu, China |
| title_sort | characteristics of urinary sodium excretion in patients with chronic kidney disease in jiangsu china |
| topic | blood pressure chronic kidney disease salt intake urinary sodium excretion |
| url | https://doi.org/10.1111/jch.14307 |
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