In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria
"nBackground and Aim: The microbial cause of dental caries has been proved among its multifactorial etiologies. The prevention and control of dental caries is very critical because of high prevalence and cost especially in high risk patient such as xerostomia. Based on the world attraction...
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| Format: | Article |
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Tehran University of Medical Sciences
2009-11-01
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| Series: | Journal of Dental Medicine |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14627.pdf&manuscript_id=14627 |
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| author | Kermanshah H. Hashemi Kamangar S. Arami S. Mirsalehian A. Kamalinejad M. Karimi M. JabalAmoli F. |
| author_facet | Kermanshah H. Hashemi Kamangar S. Arami S. Mirsalehian A. Kamalinejad M. Karimi M. JabalAmoli F. |
| author_sort | Kermanshah H. |
| collection | DOAJ |
| description | "nBackground and Aim: The microbial cause of dental caries has been proved among its multifactorial etiologies. The prevention and control of dental caries is very critical because of high prevalence and cost especially in high risk patient such as xerostomia. Based on the world attraction to traditional treatment and importance of drug extraction of natural materials and plants, in this in vitro study effect of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum which were very useful in traditional treatment of mouth and teeth disease has been determined against cariogenic bacteria. "nMaterials and Methods: In this experimental study, hydroalcoholic extracts have been prepared from Salvia officinalis and Pimpinella anisum with maceration method. Their antibacterial activity against Streptococcus mutans, Lactobacillus rhamnosus and Actinomyces viscosus have been evaluated with broth macrodilution method. Data were analyzed with Mann-Whitney test. "nResults: Minimum Inhibitory Concentration for Salvia officinalis and Pimpinella anisum for streptococcus mutans were respectively 6.25 and 12.5 µg/ml, for Lactobacillus rhamnosus were 1.56 and 12.5 µg/ml and for Actinomyces viscosus were 12.5 and 50 µg/ml. "nConclusion:Both extracts had growth inhibitory effect on all three bacteria. Salvia officinalis had significantly greater effect on inhibition of growth of all three bacteria. Both extracts had bactericidal effect in the range of concentration. |
| first_indexed | 2024-04-12T10:32:02Z |
| format | Article |
| id | doaj.art-e671d124900a46b2aec8df211b7df1f3 |
| institution | Directory Open Access Journal |
| issn | 1024-641X 2008-2444 |
| language | fas |
| last_indexed | 2024-04-12T10:32:02Z |
| publishDate | 2009-11-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Medicine |
| spelling | doaj.art-e671d124900a46b2aec8df211b7df1f32022-12-22T03:36:50ZfasTehran University of Medical SciencesJournal of Dental Medicine1024-641X2008-24442009-11-01222149154In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteriaKermanshah H.Hashemi Kamangar S.Arami S.Mirsalehian A.Kamalinejad M.Karimi M.JabalAmoli F."nBackground and Aim: The microbial cause of dental caries has been proved among its multifactorial etiologies. The prevention and control of dental caries is very critical because of high prevalence and cost especially in high risk patient such as xerostomia. Based on the world attraction to traditional treatment and importance of drug extraction of natural materials and plants, in this in vitro study effect of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum which were very useful in traditional treatment of mouth and teeth disease has been determined against cariogenic bacteria. "nMaterials and Methods: In this experimental study, hydroalcoholic extracts have been prepared from Salvia officinalis and Pimpinella anisum with maceration method. Their antibacterial activity against Streptococcus mutans, Lactobacillus rhamnosus and Actinomyces viscosus have been evaluated with broth macrodilution method. Data were analyzed with Mann-Whitney test. "nResults: Minimum Inhibitory Concentration for Salvia officinalis and Pimpinella anisum for streptococcus mutans were respectively 6.25 and 12.5 µg/ml, for Lactobacillus rhamnosus were 1.56 and 12.5 µg/ml and for Actinomyces viscosus were 12.5 and 50 µg/ml. "nConclusion:Both extracts had growth inhibitory effect on all three bacteria. Salvia officinalis had significantly greater effect on inhibition of growth of all three bacteria. Both extracts had bactericidal effect in the range of concentration.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14627.pdf&manuscript_id=14627Cariogenic BacteriaPlant ExtractAntibacterial ActivitySalvia OfficinalisPimpinella AnisumStreptococcus Mutans |
| spellingShingle | Kermanshah H. Hashemi Kamangar S. Arami S. Mirsalehian A. Kamalinejad M. Karimi M. JabalAmoli F. In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria Journal of Dental Medicine Cariogenic Bacteria Plant Extract Antibacterial Activity Salvia Officinalis Pimpinella Anisum Streptococcus Mutans |
| title | In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria |
| title_full | In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria |
| title_fullStr | In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria |
| title_full_unstemmed | In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria |
| title_short | In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Pimpinella anisum against cariogenic bacteria |
| title_sort | in vitro evaluation of antibacterial activity of hydroalcoholic extract of salvia officinalis and pimpinella anisum against cariogenic bacteria |
| topic | Cariogenic Bacteria Plant Extract Antibacterial Activity Salvia Officinalis Pimpinella Anisum Streptococcus Mutans |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/14627.pdf&manuscript_id=14627 |
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